Defining the origins of Ras/p53-mediated squamous cell carcinoma
about
Macrophages contribute to the cyclic activation of adult hair follicle stem cellsCells of origin and tumor-initiating cells for nonmelanoma skin cancersNot miR-ly micromanagers: the functions and regulatory networks of microRNAs in mammalian skinMaintaining tissue homeostasis: dynamic control of somatic stem cell activityChromatin dynamics during cellular reprogrammingCellular reprogramming in skin cancerImpact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild-type and BK5.AktWT mice.Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth.A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse.Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer.SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma.miR-125b can enhance skin tumor initiation and promote malignant progression by repressing differentiation and prolonging cell survivalEmerging interactions between skin stem cells and their niches.Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.ETS family transcriptional regulators drive chromatin dynamics and malignancy in squamous cell carcinomasRunx1 and p21 synergistically limit the extent of hair follicle stem cell quiescence in vivoInflammation and Hras signaling control epithelial-mesenchymal transition during skin tumor progression.Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells.Basal stem cells contribute to squamous cell carcinomas in the oral cavity.RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.Defining the clonal dynamics leading to mouse skin tumour initiation.Stem cell quiescence acts as a tumour suppressor in squamous tumours.Keratinocyte stem cells and the targets for nonmelanoma skin cancer.Home sweet home: skin stem cell niches.Stem cells of the human epidermis and their niche: composition and function in epidermal regeneration and carcinogenesis.Biochemistry of epidermal stem cells.Epigenetic alterations involved in cancer stem cell reprogramming.New insights into the role of Runx1 in epithelial stem cell biology and pathology.EGFR-ras-raf signaling in epidermal stem cells: roles in hair follicle development, regeneration, tissue remodeling and epidermal cancers.Epithelial stem cells in adult skin.New insights into skin stem cell aging and cancer.Heterogeneity and plasticity of epidermal stem cells.Modeling cutaneous squamous carcinoma development in the mouseRefining the role for adult stem cells as cancer cells of originTCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis.Lactate dehydrogenase activity drives hair follicle stem cell activation.Stem Cell Lineage Infidelity Drives Wound Repair and Cancer.Long-Lived Epidermal Cancer-Initiating Cells.
P2860
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P2860
Defining the origins of Ras/p53-mediated squamous cell carcinoma
description
2011 nî lūn-bûn
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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@ast
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@en
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@nl
type
label
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@ast
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@en
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@nl
prefLabel
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@ast
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@en
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@nl
P2093
P2860
P356
P1476
Defining the origins of Ras/p53-mediated squamous cell carcinoma
@en
P2093
Christine Dang
Kathy Tran
Scott W Binder
William E Lowry
Yongyan Cui
P2860
P304
P356
10.1073/PNAS.1012670108
P407
P577
2011-04-18T00:00:00Z