Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation. - Wikidata - wikimedia - TriplyDB

Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation.

Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation.

http://www.wikidata.org/entity/Q34938518

about

Hedgehog signaling pathway in ovarian cancer Decoding the phosphorylation code in Hedgehog signal transduction Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?The ciliary membrane.Advances in chemical labeling of proteins in living cells Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened Functional characterization of putative cilia genes by high-content analysis A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity Subcellular localization of Patched and Smoothened, the receptors for Sonic hedgehog signaling, in the hippocampal neuron Hedgehog signaling is required at multiple stages of zebrafish tooth development Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding.The future of ciliary and flagellar membrane research.Hedgehog signaling controls T cell killing at the immunological synapse.Coordinated translocation of mammalian Gli proteins and suppressor of fused to the primary cilium Chemical and biological studies of nakiterpiosin and nakiterpiosinone.Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells.Mechanism and evolution of cytosolic Hedgehog signal transduction Simultaneous measurement of smoothened entry into and exit from the primary cilium.Small-molecule modulators of the Sonic Hedgehog signaling pathway.Cilia in the CNS: the quiet organelle claims center stage Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation.NL-103, a novel dual-targeted inhibitor of histone deacetylases and hedgehog pathway, effectively overcomes vismodegib resistance conferred by Smo mutations.Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.Arl13b regulates endocytic recycling traffic.Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome.Hedgehog-regulated atypical PKC promotes phosphorylation and activation of Smoothened and Cubitus interruptus in Drosophila.The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation.Discovery of small-molecule modulators of the Sonic Hedgehog pathway.Enthesis fibrocartilage cells originate from a population of Hedgehog-responsive cells modulated by the loading environment.Heterotrimeric Gi proteins link Hedgehog signaling to activation of Rho small GTPases to promote fibroblast migration.Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis.Clinical implications of hedgehog signaling pathway inhibitors Endocannabinoids are conserved inhibitors of the Hedgehog pathway.

P2860

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P2860

Selective translocation of intracellular Smoothened to the primary cilium in response to Hedgehog pathway modulation.

http://www.wikidata.org/entity/Q34938518

description

2009 nî lūn-bûn

@nan

2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

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2009年学术文章

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2009年學術文章

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name

Selective translocation of int ...... o Hedgehog pathway modulation.

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Selective translocation of int ...... o Hedgehog pathway modulation.

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Selective translocation of int ...... o Hedgehog pathway modulation.

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type

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Selective translocation of int ...... o Hedgehog pathway modulation.

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Selective translocation of int ...... o Hedgehog pathway modulation.

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Selective translocation of int ...... o Hedgehog pathway modulation.

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Selective translocation of int ...... o Hedgehog pathway modulation.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Selective translocation of int ...... o Hedgehog pathway modulation.

@en

P2093

Andrew P McMahon

http://www.w3.org/2001/XMLSchema#string

Christopher T Walsh

http://www.w3.org/2001/XMLSchema#string

Yu Wang

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Zhe Zhou

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P2860

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

Activating Smoothened mutations in sporadic basal-cell carcinoma

Small molecule modulation of Smoothened activity

Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells

Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes

Assembly of centrosomal proteins and microtubule organization depends on PCM-1

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

Vertebrate Smoothened functions at the primary cilium.

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2623-2628

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106

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19196978

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2650314

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