Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions.
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Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic StrategiesProtein kinase D enzymes: novel kinase targets in pancreatic cancerSystems biology approach to developing S(2)RM-based "systems therapeutics" and naturally induced pluripotent stem cellsThe Presence of Interleukin-13 at Pancreatic ADM/PanIN Lesions Alters Macrophage Populations and Mediates Pancreatic TumorigenesisMutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions.BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation.Genetically Engineered Mouse Models of Pancreatic Cancer: The KPC Model (LSL-Kras(G12D/+) ;LSL-Trp53(R172H/+) ;Pdx-1-Cre), Its Variants, and Their Application in Immuno-oncology Drug Discovery.Pancreatic cancer: from bench to bedside.Tumour-derived Interleukin 35 promotes pancreatic ductal adenocarcinoma cell extravasation and metastasis by inducing ICAM1 expression.Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancerChemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors.What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?Emerging cytokine networks in colorectal cancer.Macrophages and pancreatic ductal adenocarcinoma.Acinar cell plasticity and development of pancreatic ductal adenocarcinoma.Redirecting the focus of cancer immunotherapy to premalignant conditions.Peritumoral stromal neutrophils are essential for c-Met-elicited metastasis in human hepatocellular carcinoma.Inflammatory macrophages in pancreatic acinar cell metaplasia and initiation of pancreatic cancer.Inducible RasGEF1B circular RNA is a positive regulator of ICAM-1 in the TLR4/LPS pathway.γδ T Cells Support Pancreatic Oncogenesis by Restraining αβ T Cell Activation.The crosstalk between acinar cells with Kras mutations and M1-polarized macrophages leads to initiation of pancreatic precancerous lesionsRole of liver ICAM-1 in metastasis.Immunologic and Metabolic Features of Pancreatic Ductal Adenocarcinoma Define Prognostic Subtypes of Disease.Epithelial-Myeloid cell crosstalk regulates acinar cell plasticity and pancreatic remodeling in mice.Extracellular Influences: Molecular Subclasses and the Microenvironment in Pancreatic Cancer.Inflammatory Cytokine Signaling during Development of Pancreatic and Prostate Cancers.Macrophages: Key orchestrators of a tumor microenvironment defined by therapeutic resistance.Jumonji AT-rich interactive domain 1B promotes the growth of pancreatic tumors via the phosphatase and tensin homolog/protein kinase B signaling pathway.Oncolytic Immunotherapy for Bladder Cancer Using Coxsackie A21 Virus.KRAS mutation and epithelial-macrophage interplay in pancreatic neoplastic transformationPlacental Ras Regulates Inflammation Associated with Maternal Obesity
P2860
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P2860
Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions.
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@ast
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@en
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@nl
type
label
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@ast
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@en
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@nl
prefLabel
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@ast
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@en
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@nl
P2093
P2860
P1433
P1476
Mutant KRAS-induced expression ...... ation of precancerous lesions.
@en
P2093
Brandy Edenfield
Brian Necela
David W Dawson
Geou-Yarh Liou
Heike Döppler
Lizhi Zhang
Peter Storz
P2860
P356
10.1158/2159-8290.CD-14-0474
P577
2014-10-31T00:00:00Z