DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein - Wikidata - wikimedia - TriplyDB

DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

http://www.wikidata.org/entity/Q34947481

about

The DGCR8 RNA-binding heme domain recognizes primary microRNAs by clamping the hairpin Processing of microRNA primary transcripts requires heme in mammalian cells Biogenesis and mechanism of action of small non-coding RNAs: insights from the point of view of structural biology Dimerization and Heme Binding Are Conserved in Amphibian and Starfish Homologues of the microRNA Processing Protein DGCR8 Unusual Spectroscopic and Ligand Binding Properties of the Cytochrome P450-Flavodoxin Fusion Enzyme XplA A heme-binding domain controls regulation of ATP-dependent potassium channels.MicroRNAs as potential therapeutics for treating spinal cord injury.Deformability in the cleavage site of primary microRNA is not sensed by the double-stranded RNA binding domains in the microprocessor component DGCR8 Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing.Caspases cleave and inhibit the microRNA processing protein DiGeorge Critical Region 8.Cobalt(III) Protoporphyrin Activates the DGCR8 Protein and Can Compensate microRNA Processing Deficiency.Primary microRNA processing assay reconstituted using recombinant Drosha and DGCR8.The heme-p53 interaction: Linking iron metabolism to p53 signaling and tumorigenesis.The core microprocessor component DiGeorge syndrome critical region 8 (DGCR8) is a nonspecific RNA-binding protein.Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile.Regulation of iron homeostasis by microRNAs.Heme sensor proteins.Human RNAi pathway: crosstalk with organelles and cells.Regulatory Fe(II/III) heme: the reconstruction of a molecule's biography.Epigenetics-related genes in prostate cancer: expression profile in prostate cancer tissues, androgen-sensitive and -insensitive cell lines.CO and NO bind to Fe(II) DiGeorge critical region 8 heme but do not restore primary microRNA processing activity.Fractional transfer of a free unpaired electron to overcome energy barriers in the formation of Fe(4+) from Fe(3+) during the core contraction of macrocycles: implication for heme distortion.Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs.Impairing the microRNA biogenesis pathway induces proteome modifications characterized by size bias and enrichment in antioxidant proteins.Microprocessor depends on hemin to recognize the apical loop of primary microRNA.

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DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

http://www.wikidata.org/entity/Q34947481

description

2011 nî lūn-bûn

@nan

2011 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

@ast

DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

@en

DiGeorge critical region 8

@nl

type

label

DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

@ast

DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

@en

DiGeorge critical region 8

@nl

prefLabel

DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

@ast

DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

@en

DiGeorge critical region 8

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P356

JBC.M110.180844

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Journal of Biological Chemistry

P1476

DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein

@en

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Aaron T Smith

http://www.w3.org/2001/XMLSchema#string

Brooke D Scheidemantle

http://www.w3.org/2001/XMLSchema#string

Feng Guo

http://www.w3.org/2001/XMLSchema#string

Judith N Burstyn

http://www.w3.org/2001/XMLSchema#string

Rachel Senturia

http://www.w3.org/2001/XMLSchema#string

Yanqiu Chen

http://www.w3.org/2001/XMLSchema#string

P2860

The nuclear RNase III Drosha initiates microRNA processing

The Microprocessor complex mediates the genesis of microRNAs

The Drosha-DGCR8 complex in primary microRNA processing

MicroRNA biogenesis: there's more than one way to skin a cat

ExPASy: The proteomics server for in-depth protein knowledge and analysis

Structure of the dimerization domain of DiGeorge Critical Region 8

His64(E7)-->Tyr apomyoglobin as a reagent for measuring rates of hemin dissociation

Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin

Processing of primary microRNAs by the Microprocessor complex

Biogenesis of small RNAs in animals

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16716-16725

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scholarly article

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10.1074/JBC.M110.180844

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19

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286

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2011-03-21T00:00:00Z

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21454614

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3089513

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