LRP1 shedding in human brain: roles of ADAM10 and ADAM17. - Wikidata - wikimedia - TriplyDB

LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

http://www.wikidata.org/entity/Q34976135

about

LRP-1: a checkpoint for the extracellular matrix proteolysis Low Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell Function Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1 The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease Cerebrospinal fluid peptides as potential Parkinson disease biomarkers: a staged pipeline for discovery and validation.Proteolytic processing of Alzheimer's β-amyloid precursor protein LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages Apolipoprotein E isoform-specific effects on lipoprotein receptor processing.Multifaceted Roles of Metzincins in CNS Physiology and Pathology: From Synaptic Plasticity and Cognition to Neurodegenerative Disorders A functional role for ADAM10 in human immunodeficiency virus type-1 replication Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function.Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.Amyloid-beta transporter expression at the blood-CSF barrier is age-dependent.Neurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's disease Low-density lipoprotein receptor-related protein 1: a physiological Aβ homeostatic mechanism with multiple therapeutic opportunities.SheddomeDB: the ectodomain shedding database for membrane-bound shed markers.Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family.Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1.LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.Schwann cell LRP1 regulates remak bundle ultrastructure and axonal interactions to prevent neuropathic pain.Oxidative stress and β-amyloid protein in Alzheimer's disease.Insights into the activity, differential expression, mutual regulation, and functions of matrix metalloproteinases and a disintegrin and metalloproteinases in hypertension and cardiac disease.Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease.Cerebrospinal fluid secretion by the choroid plexus.Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.Role of LRP1 in the pathogenesis of Alzheimer's disease: evidence from clinical and preclinical studies.Verification and characterization of an alternative low density lipoprotein receptor-related protein 1 splice variant.Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling.Extracellular vesicles do not contribute to higher circulating levels of soluble LRP1 in idiopathic dilated cardiomyopathy.Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuroinflammation.T-cell regulation through a basic suppressive mechanism targeting low-density lipoprotein receptor-related protein 1.Shedding of low-density lipoprotein receptor–related protein-1 in acute respiratory distress syndrome.

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P2860

LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

http://www.wikidata.org/entity/Q34976135

description

2009 nî lūn-bûn

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2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2009 թվականի ապրիլին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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Molecular Neurodegeneration

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LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

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Guojun Bu

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Hien Tran

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Juan Zhang

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Karina Reiss

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Marcel M Verbeek

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Qiang Liu

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Steven Estus

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P2860

Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1

Proteolytic processing of the 600 kd low density lipoprotein receptor-related protein (LRP) occurs in a trans-Golgi compartment

39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein

The amyloid precursor protein: beyond amyloid

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Soluble low density lipoprotein receptor-related protein (LRP) circulates in human plasma

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

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17

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19371428

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