Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells

Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells

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http://www.wikidata.org/entity/Q34977484
Sirtuins and Cancer: Role in the Epithelial-Mesenchymal TransitionPro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling patThe investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cellsNovel targeting of PEGylated liposomes for codelivery of TGF-β1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study.Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.Small putative NANOG, SOX2, and SSEA-4-positive stem cells resembling very small embryonic-like stem cells in sections of ovarian tissue in patients with ovarian cancerAlisertib induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt/mTOR- and p38 MAPK-mediated pathways in human glioblastoma cellsPlumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.A SILAC-based proteomics elicits the molecular interactome of alisertib (MLN8237) in human erythroleukemia K562 cells.A proteomics-based investigation on the anticancer activity of alisertib, an Aurora kinase A inhibitor, in hepatocellular carcinoma Hep3B cells.Kinases Involved in Both Autophagy and Mitosis.Silencing Aurora A leads to re-sensitization of breast cancer cells to Taxol through downregulation of SRC-mediated ERK and mTOR pathways.The CNS penetrating taxane TPI 287 and the AURKA inhibitor alisertib induce synergistic apoptosis in glioblastoma cells.A quantitative proteomic response of hepatocellular carcinoma Hep3B cells to danusertib, a pan-Aurora kinase inhibitor.
P2860

Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cells

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http://www.wikidata.org/entity/Q34977484
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2015 nî lūn-bûn
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2015年の論文
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2015年論文
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Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@ast
Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@en
Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@nl
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Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@ast
Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@en
Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@nl
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Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@ast
Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@en
Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P478
P577
P698
P921
P932
P356
P1433
P1476
Alisertib, an Aurora kinase A ...... pithelial ovarian cancer cells
@en
P2093
P2860
P304
P31
P356
P407
P478
P577
P698
P921
P932