Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
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Fundamentals of cancer metabolismCancer Metabolism: A Modeling PerspectiveHypoxia and metabolic adaptation of cancer cellsAlternative fuels for cancer cellsA rapid method for quantifying free and bound acetate based on alkylation and GC-MS analysisUndercover: gene control by metabolites and metabolic enzymesLipid Droplets: A Key Cellular Organelle Associated with Cancer Cell Survival under Normoxia and HypoxiaOncometabolites: tailoring our genesMetabolic pathways promoting cancer cell survival and growthMetformin Decouples Phospholipid Metabolism in Breast Cancer CellsA joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer.Non-invasive metabolic imaging of brain tumours in the era of precision medicine.Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γFASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and GMycobacterial heat shock protein 65 mediated metabolic shift in decidualization of human endometrial stromal cellsDecreased expression of acetyl-CoA synthase 2 promotes metastasis and predicts poor prognosis in hepatocellular carcinoma.Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolismmTORC2 activity in brain cancer: Extracellular nutrients are required to maintain oncogenic signaling.Attacking the supply wagons to starve cancer cells to death.Antitumor/Antifungal Celecoxib Derivative AR-12 is a Non-Nucleoside Inhibitor of the ANL-Family Adenylating Enzyme Acetyl CoA Synthetase.The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis.OECI-EACR precision medicine for cancer: Conference report 1-4 March 2015, Luxembourg.The metabolic fate of acetate in cancer.Purification, characterization and crystallization of the F-ATPase from Paracoccus denitrificansCancer's Fuel Choice: New Flavors for a Picky EaterGenome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.The Emerging Hallmarks of Cancer MetabolismCharacterisation of bioenergetic pathways and related regulators by multiple assays in human tumour cells.Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells.Bonded Cumomer Analysis of Human Melanoma Metabolism Monitored by 13C NMR Spectroscopy of Perfused Tumor CellsBridging the gap between non-targeted stable isotope labeling and metabolic flux analysis.Reductive carboxylation supports redox homeostasis during anchorage-independent growth.(13)C MRS and LC-MS Flux Analysis of Tumor Intermediary Metabolism.Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma.Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia.Three-dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 modelThe novel choline kinase inhibitor ICL-CCIC-0019 reprograms cellular metabolism and inhibits cancer cell growth.Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma.Tumour microenvironment factors shaping the cancer metabolism landscape.Altered Mitochondrial Signalling and Metabolism in Cancer.
P2860
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P2860
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@ast
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@en
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@nl
type
label
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@ast
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@en
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@nl
prefLabel
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@ast
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@en
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@nl
P2093
P2860
P50
P1433
P1476
Acetyl-CoA synthetase 2 promot ...... growth under metabolic stress
@en
P2093
Bradley Spencer-Dene
Daniel James
Dylan T Jones
Elizabeth Smethurst
Eric O Aboagye
Francois Lassailly
Gabriela Kalna
Gillian Mackay
Gordon Stamp
Israt S Alam
P2860
P356
10.1016/J.CCELL.2014.12.002
P50
P577
2015-01-01T00:00:00Z