Telomere attrition and Chk2 activation in human heart failure - Wikidata - wikimedia - TriplyDB

Telomere attrition and Chk2 activation in human heart failure

Telomere attrition and Chk2 activation in human heart failure

http://www.wikidata.org/entity/Q34983035

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BRCA1 is an essential regulator of heart function and survival following myocardial infarction Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2 Role of Telomerase in the Cardiovascular System Oxidative stress-induced telomeric erosion as a mechanism underlying airborne particulate matter-related cardiovascular disease Effects of biological sex on the pathophysiology of the heart Telomere shortening in human diseases Telomeres and Telomerase in Cardiovascular Diseases Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy Telomeres and early-life stress: an overview Telomerase Is Essential for Zebrafish Heart Regeneration Telomere biology in healthy aging and disease.Unchain my heart: the scientific foundations of cardiac repair Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Aging, telomeres and heart failure.Beyond average: potential for measurement of short telomeres.Telomere biology in cardiovascular disease - role of insulin sensitivity in diabetic hearts.Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis DNA damage checkpoint kinase Chk2 triggers replicative senescence.Telomeres, telomerase, and apoptosis.Death begets failure in the heart.Cardiac stem cells and mechanisms of myocardial regeneration.Telomerase expression in the mammalian heart Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase.Telomere dynamics during aging in polygenic left ventricular hypertrophy.DNA damage accumulation and TRF2 degradation in atypical Werner syndrome fibroblasts with LMNA mutations.Telomeres and mitochondria in the aging heart.Sirt1 protects the heart from aging and stress.Telomerase confers resistance to caspase-mediated apoptosis.Telomere biology in heart failure.Identification of small juvenile stem cells in aged bone marrow and their therapeutic potential for repair of the ischemic heart.Renal dysfunction is associated with shorter telomere length in heart failure.Prevention of heart failure in the elderly: when, where and how to begin?Stem cell therapy for cardiac disease.Age related cardiovascular dysfunction and effects of physical activity.Telomere, aging and age-related diseases.The influence of the telomere-telomerase system on diabetes mellitus and its vascular complications.Evaluation of telomere length in human cardiac tissues using cardiac quantitative FISH.Cardiac telomere length in heart development, function, and disease.Telomere length and psychological well-being in patients with chronic heart failure.

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P2860

Telomere attrition and Chk2 activation in human heart failure

http://www.wikidata.org/entity/Q34983035

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2003 nî lūn-bûn

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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2003 թվականի ապրիլին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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Telomere attrition and Chk2 activation in human heart failure

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Telomere attrition and Chk2 activation in human heart failure

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Proceedings of the National Academy of Sciences of the United States of America

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Telomere attrition and Chk2 activation in human heart failure

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Arun Prahash

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Christine S Moravec

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George E Taffet

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Hidemasa Oh

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Keith A Youker

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Lloyd H Michael

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Mark L Entman

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Michael D Schneider

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Motoaki Sano

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Sam C Wang

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P2860

Mammalian telomeres end in a large duplex loop

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases

Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells

A simplified system for generating recombinant adenoviruses

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival

Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

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5378-5383

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