Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. - Wikidata - wikimedia - TriplyDB

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

http://www.wikidata.org/entity/Q34983386

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Chondroitin sulfate proteoglycans in the nervous system: inhibitors to repair Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor- alpha Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease Serum antibodies from Parkinson's disease patients react with neuronal membrane proteins from a mouse dopaminergic cell line and affect its dopamine expression Cellular and molecular mediators of neuroinflammation in the pathogenesis of Parkinson's disease The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?Role of prostaglandins in neuroinflammatory and neurodegenerative diseases Therapeutic potential of monoacylglycerol lipase inhibitors Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity Are cyclooxygenase-2 and nitric oxide involved in the dyskinesia of Parkinson's disease induced by L-DOPA?Immunomodulatory Effects Mediated by Dopamine Effect of steroidal and non-steroidal drugs on the microglia activation pattern and the course of degeneration in the retinal degeneration slow mouse Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia Formation and Biological Targets of Quinones: Cytotoxic versus Cytoprotective Effects Striatal neuroinflammation promotes Parkinsonism in rats Mining relational paths in integrated biomedical data Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism Cytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death.Arachidonic acid metabolism in brain physiology and pathology: lessons from genetically altered mouse models Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson's disease.Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.Molecular fingerprinting of radiation resistant tumors: can we apprehend and rehabilitate the suspects?Diverse methyl sulfone-containing benzo[b]thiophene library via iodocyclization and palladium-catalyzed coupling.Neuron-selective changes in RNA transcripts related to energy metabolism in toxic models of parkinsonism in rodents.Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention SNJ-1945, a calpain inhibitor, protects SH-SY5Y cells against MPP(+) and rotenone.In situ click chemistry generation of cyclooxygenase-2 inhibitors.Cyclooxygenase and neuroinflammation in Parkinson's disease neurodegeneration.Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1.Cyclopentenone eicosanoids as mediators of neurodegeneration: a pathogenic mechanism of oxidative stress-mediated and cyclooxygenase-mediated neurotoxicity.The effects of piroxicam in the attenuation of MPP+/MPTP toxicity in vitro and in vivo.Defining a role for hemoglobin in Parkinson's disease Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease.Neuronal overexpression of cyclooxygenase-2 does not alter the neuroinflammatory response during brain innate immune activation.Role of microglia adenosine A(2A) receptors in retinal and brain neurodegenerative diseases.Adaptive immune regulation of glial homeostasis as an immunization strategy for neurodegenerative diseases Glial cell line-derived neurotrophic factor protects midbrain dopaminergic neurons against lipopolysaccharide neurotoxicity.Apoptosis signal-regulating kinase 1 mediates MPTP toxicity and regulates glial activation.

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P2860

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

http://www.wikidata.org/entity/Q34983386

description

2003 nî lūn-bûn

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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

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type

label

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

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prefLabel

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

@ast

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

@en

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

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PNAS.0837397100

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Proceedings of the National Academy of Sciences of the United States of America

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Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration.

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P2093

Ali Naini

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Du-Chu Wu

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Peter Teismann

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P2860

COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression

Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology

Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct.

The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety.

Prostaglandin and thromboxane biosynthesis.

Mixed lineage kinase activity of indolocarbazole analogues.

Overexpression of cyclooxygenase-2 induces cell cycle arrest. Evidence for a prostaglandin-independent mechanism.

Ceramide regulates the transcription of cyclooxygenase-2. Evidence for involvement of extracellular signal-regulated kinase/c-Jun N-terminal kinase and p38 mitogen-activated protein kinase pathways.

Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy.

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100

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Stéphane Hunot

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Parkinson's disease

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