Conformational mAb as a tool for integrin ligand discovery
about
Discovery of very late antigen-4 (VLA-4, alpha4beta1 integrin) allosteric antagonists.Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization.Drug Repurposing from an Academic Perspective.Overview: assays for studying integrin-dependent cell adhesion.Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion.Development of cell-penetrating bispecific antibodies targeting the N-terminal domain of androgen receptor for prostate cancer therapy.
P2860
Q33763221-BD649DF0-30C3-4CD4-A831-B97FCC56355FQ33903491-8708991E-3AA4-462E-8D44-872F4392F6CEQ35063491-EA4DD010-DDBF-43E1-9CD2-706EFD5C1A38Q35390252-CC023B71-089A-462E-9FE1-B42E1B294F08Q35774211-A3D931DF-6B13-4AFF-9A4A-4AA77D9F3876Q37930496-F81C5F51-F553-4799-9BCC-9E97A61EF268Q42051797-11CD3635-761B-4F83-B77C-BD11B2D3CA5DQ47307286-84FE7752-2077-45C1-9AB1-860462F9C7F7
P2860
Conformational mAb as a tool for integrin ligand discovery
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Conformational mAb as a tool for integrin ligand discovery
@ast
Conformational mAb as a tool for integrin ligand discovery
@en
Conformational mAb as a tool for integrin ligand discovery
@nl
type
label
Conformational mAb as a tool for integrin ligand discovery
@ast
Conformational mAb as a tool for integrin ligand discovery
@en
Conformational mAb as a tool for integrin ligand discovery
@nl
prefLabel
Conformational mAb as a tool for integrin ligand discovery
@ast
Conformational mAb as a tool for integrin ligand discovery
@en
Conformational mAb as a tool for integrin ligand discovery
@nl
P2093
P2860
P356
P1476
Conformational mAb as a tool for integrin ligand discovery
@en
P2093
Alexandre Chigaev
Anna Waller
Ben H Njus
Cristian G Bologa
Danuta Wlodek
Larry A Sklar
Liliana Ostopovici-Halip
Tudor I Oprea
P2860
P304
P356
10.1089/ADT.2009.0203
P577
2009-10-01T00:00:00Z