Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses - Wikidata - wikimedia - TriplyDB

Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses

Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses

http://www.wikidata.org/entity/Q28371157

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Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells The integrin alphavbeta3 is a receptor for the latency-associated peptides of transforming growth factors beta1 and beta3 Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior COX-2 inhibitors vs. NSAIDs in gastrointestinal damage and prevention Alpha4 integrins and the immune response Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1.Small molecule agonist of very late antigen-4 (VLA-4) integrin induces progenitor cell adhesion Galphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion.Integrins as Therapeutic Targets for Respiratory Diseases Therapeutic strategies for allergic diseases.Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.Novel therapy for asthma.A 3D structure model of integrin alpha 4 beta 1 complex: I. Construction of a homology model of beta 1 and ligand binding analysis FRET detection of cellular alpha4-integrin conformational activation.Drugs, inflammation and cell adhesion receptors.Antiadhesion molecule therapy in inflammatory bowel disease.T lymphocytes in food allergy: overview of an intricate network of circulating and organ-resident cells.Conformational mAb as a tool for integrin ligand discovery Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization.Actual therapeutic management of allergic and hyperreactive nasal disorders 5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists.Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis.Alpha-4/beta-1 and alpha-L/beta-2 integrins mediate cytokine induced lung leukocyte-epithelial adhesion and injury Lymphocyte trafficking to inflamed skin--molecular mechanisms and implications for therapeutic target molecules.Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain Mobilization of hematopoietic stem and progenitor cells using inhibitors of CXCR4 and VLA-4.Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma.Overview: assays for studying integrin-dependent cell adhesion.Role of integrin alpha4 in drug resistance of leukemia Quantification of integrin receptor agonism by fluorescence lifetime imaging.Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects.Measurement of VLA-4/CS-1 and VLA-4/VCAM adhesion inhibition.Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation.Potent cyclic monomeric and dimeric peptide inhibitors of VLA-4 (alpha4beta1 integrin)-mediated cell adhesion based on the Ile-Leu-Asp-Val tetrapeptide.Integrins as Therapeutic Targets: Successes and Cancers.Dehydro-β-proline Containing α4β1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay.Conformational regulation of the fibronectin binding and alpha 3beta 1 integrin-mediated adhesive activities of thrombospondin-1.

P2860

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P2860

Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses

http://www.wikidata.org/entity/Q28371157

description

1999 nî lūn-bûn

@nan

1999 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի մարտին հրատարակված գիտական հոդված

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1999年の論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年論文

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1999年论文

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name

Selective, tight-binding inhib ...... ibit allergic airway responses

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Selective, tight-binding inhib ...... ibit allergic airway responses

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Selective, tight-binding inhib ...... ibit allergic airway responses

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type

label

Selective, tight-binding inhib ...... ibit allergic airway responses

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Selective, tight-binding inhib ...... ibit allergic airway responses

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Selective, tight-binding inhib ...... ibit allergic airway responses

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prefLabel

Selective, tight-binding inhib ...... ibit allergic airway responses

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Selective, tight-binding inhib ...... ibit allergic airway responses

@en

Selective, tight-binding inhib ...... ibit allergic airway responses

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P1433

Journal of Medicinal Chemistry

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Selective, tight-binding inhib ...... ibit allergic airway responses

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P2093

A Castro

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A G Sprague

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A Gill

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C E Hammond

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C N Zimmerman

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D R Leone

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H S Ateeq

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K c Lin

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L L Chen

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L T Chong

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920-34

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scholarly article

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10.1021/JM980673G

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5

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42

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1999-03-11T00:00:00Z

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10072689

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