The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells. - Wikidata - wikimedia - TriplyDB

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

http://www.wikidata.org/entity/Q34989042

about

Ubiquitin in the immune system Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases?A Kinetic Study of CD83 Reveals an Upregulation and Higher Production of sCD83 in Lymphocytes from Pregnant Mice GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A Continuous expression of CD83 on activated human CD4⁺ T cells is correlated with their differentiation into induced regulatory T cells Global comparison of chromosome X genes of pulmonary telocytes with mesenchymal stem cells, fibroblasts, alveolar type II cells, airway epithelial cells, and lymphocytes.GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation.Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation.Grail as a molecular determinant for the functions of the tumor suppressor p53 in tumorigenesis.Upregulation of GRAIL is associated with impaired CD4 T cell proliferation in sepsis.GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness.RNF13: an emerging RING finger ubiquitin ligase important in cell proliferation.The Role of the Transmembrane RING Finger Proteins in Cellular and Organelle Function E3 ubiquitin ligase RNF128 promotes innate antiviral immunity through K63-linked ubiquitination of TBK1.Targeting CD83 for the treatment of graft-versus-host disease.Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization.CRYAB modulates the activation of CD4+ T cells from relapsing-remitting multiple sclerosis patients.Regulation of anergy-related ubiquitin E3 ligase, GRAIL, in murine models of colitis and patients with Crohn's disease.

P2860

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P2860

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

http://www.wikidata.org/entity/Q34989042

description

2009 nî lūn-bûn

@nan

2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@ast

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@en

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@nl

type

label

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@ast

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@en

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@nl

prefLabel

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@ast

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@en

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@nl

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P932

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P356

JIMMUNOL.0900204

P1433

Journal of Immunology

P1476

The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.

@en

P2093

C Garrison Fathman

http://www.w3.org/2001/XMLSchema#string

Hideyuki Iwai

http://www.w3.org/2001/XMLSchema#string

Jack T Lin

http://www.w3.org/2001/XMLSchema#string

Leon L Su

http://www.w3.org/2001/XMLSchema#string

P2860

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

Cutting edge: The transmembrane E3 ligase GRAIL ubiquitinates the costimulatory molecule CD40 ligand during the induction of T cell anergy

Mechanisms underlying ubiquitination

GRAIL: an E3 ubiquitin ligase that inhibits cytokine gene transcription is expressed in anergic CD4+ T cells

Two isoforms of otubain 1 regulate T cell anergy via GRAIL

Crystal structure of a soluble CD28-Fab complex

Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.

c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.

Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance.

Prevention and treatment of experimental autoimmune encephalomyelitis by soluble CD83

P304

438-444

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scholarly article

P356

10.4049/JIMMUNOL.0900204

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P407

P433

1

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P478

183

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P577

2009-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26307194

http://www.w3.org/2001/XMLSchema#string

P698

19542455

http://www.w3.org/2001/XMLSchema#string

P921

protein ubiquitination

transmembrane protein

P932

4300110

http://www.w3.org/2001/XMLSchema#string