Protein prenylation: enzymes, therapeutics, and biotechnology applications.
about
Enzymatic prenylation and oxime ligation for the synthesis of stable and homogeneous protein-drug conjugates for targeted therapyS-Geranyl-2-thiouridine wobble nucleosides of bacterial tRNAs; chemical and enzymatic synthesis of S-geranylated-RNAs and their physicochemical characterizationGlobal proteomic analysis of prenylated proteins in Plasmodium falciparum using an alkyne-modified isoprenoid analogueFunctional analysis of the zebrafish ortholog of HMGCS1 reveals independent functions for cholesterol and isoprenoids in craniofacial development.Simvastatin suppresses breast cancer cell proliferation induced by senescent cellsStructural basis for non-genuine phenolic acceptor substrate specificity of Streptomyces roseochromogenes prenyltransferase CloQ from the ABBA/PT-barrel superfamilyA lack of 'glue' misplaces Rab27A to cause islet dysfunction in diabetesSynthetic isoprenoid analogues for the study of prenylated proteins: Fluorescent imaging and proteomic applications.Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis.Nitrodibenzofuran: A One- and Two-Photon Sensitive Protecting Group That Is Superior to Brominated Hydroxycoumarin for Thiol Caging in PeptidesSynthesis of Peptides Containing C-Terminal Esters Using Trityl Side-Chain Anchoring: Applications to the Synthesis of C-Terminal Ester Analogs of the Saccharomyces cerevisiae Mating Pheromone a-FactorMolecular basis for the broad substrate selectivity of a peptide prenyltransferase.Prenyltransferases as key enzymes in primary and secondary metabolism.Olefin Isomers of a Triazole Bisphosphonate Synergistically Inhibit Geranylgeranyl Diphosphate Synthase.Cancer Chemotherapy Specific to Acidic Nests.Hepatitis Delta Virus: Replication Strategy and Upcoming Therapeutic Options for a Neglected Human Pathogen.Statins Modulate Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 in Human Hepatic Myofibroblasts.6-Bromo-7-hydroxy-3-methylcoumarin (mBhc) is an efficient multi-photon labile protecting group for thiol caging and three-dimensional chemical patterning.Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation.Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation.RAB geranylgeranylationRAB GEFs exchange GTP for GDP on RABsa-Factor Analogues Containing Alkyne- and Azide-Functionalized Isoprenoids Are Efficiently Enzymatically Processed and Retain Wild-Type Bioactivity.Development of the Regiodivergent Asymmetric Prenylation of 3-Substituted Oxindoles.Bishomoisoprenoid triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase.Extensive molecular tinkering in the evolution of the membrane attachment mode of the Rheb GTPase.a-Factor: a chemical biology tool for the study of protein prenylation.
P2860
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P2860
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@ast
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@en
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@nl
type
label
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@ast
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@en
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@nl
prefLabel
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@ast
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@en
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@nl
P2860
P921
P356
P1433
P1476
Protein prenylation: enzymes, therapeutics, and biotechnology applications.
@en
P2093
Charuta C Palsuledesai
Mark D Distefano
P2860
P356
10.1021/CB500791F
P577
2014-12-08T00:00:00Z
2015-01-16T00:00:00Z