Structure of mammalian protein geranylgeranyltransferase type-I - Wikidata - wikimedia - TriplyDB

Structure of mammalian protein geranylgeranyltransferase type-I

Structure of mammalian protein geranylgeranyltransferase type-I

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Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation Refinement and prediction of protein prenylation motifs Structure of Protein Geranylgeranyltransferase-I from the Human Pathogen Candida albicans Complexed with a Lipid Substrate Structural Basis for Binding and Selectivity of Antimalarial and Anticancer Ethylenediamine Inhibitors to Protein Farnesyltransferase Synthesis, Properties, and Applications of Diazotrifluropropanoyl-Containing Photoactive Analogs of Farnesyl Diphosphate Containing Modified Linkages for Enhanced Stability Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens Multiple domain insertions and losses in the evolution of the Rab prenylation complex.Inhibitors of protein geranylgeranyltransferase I and Rab geranylgeranyltransferase identified from a library of allenoate-derived compounds.Enlarged meristems and delayed growth in plp mutants result from lack of CaaX prenyltransferases.The CaaX specificities of Arabidopsis protein prenyltransferases explain era1 and ggb phenotypes Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases A novel approach to tag and identify geranylgeranylated proteins.Protein Lipidation As a Regulator of Apoptotic Calcium Release: Relevance to Cancer.Therapeutic intervention based on protein prenylation and associated modifications Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92 Protein prenylation: enzymes, therapeutics, and biotechnology applications.HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells.Exploration of GGTase-I substrate requirements. Part 1: Synthesis and biochemical evaluation of novel aryl-modified geranylgeranyl diphosphate analogs.Exploration of GGTase-I substrate requirements. Part 2: Synthesis and biochemical analysis of novel saturated geranylgeranyl diphosphate analogs.Thematic review series: lipid posttranslational modifications. geranylgeranylation of Rab GTPases.Protein geranylgeranyltransferase-I of Trypanosoma cruzi.Simultaneous Site-Specific Dual Protein Labeling Using Protein Prenyltransferases.Phosphonocarboxylates inhibit the second geranylgeranyl addition by Rab geranylgeranyl transferase.Impaired geranylgeranyltransferase-I regulation reduces membrane-associated Rho protein levels in aged mouse brain.Module assembly for designing multivalent mid-sized inhibitors of protein-protein interactions.Prenyltransferase Inhibitors: Treating Human Ailments from Cancer to Parasitic Infections.The Role of Geranylgeranyltransferase I-Mediated Protein Prenylation in the Brain.Geranylgeranyltransferase I promotes human glioma cell growth through Rac1 membrane association and activation.Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication.Molecular docking and simulation of Curcumin with Geranylgeranyl Transferase1 (GGTase1) and Farnesyl Transferase (FTase).Catalytic mechanism of aromatic prenylation by NphB.Mutational analysis of the integral membrane methyltransferase isoprenylcysteine carboxyl methyltransferase (ICMT) reveals potential substrate binding sites.Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cells.Metals in proteins: cluster analysis studies.Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium.Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum.The crystal structure of (S)-3-O-geranylgeranylglyceryl phosphate synthase reveals an ancient fold for an ancient enzyme.Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.Recognition and stabilization of geranylgeranylated human Rab5 by the GDP Dissociation Inhibitor (GDI).Cyclase-Associated Protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase.

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P2860

Structure of mammalian protein geranylgeranyltransferase type-I

http://www.wikidata.org/entity/Q24644688

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2003 nî lūn-bûn

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2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2003 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2003年の論文

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name

Structure of mammalian protein geranylgeranyltransferase type-I

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Structure of mammalian protein geranylgeranyltransferase type-I

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Structure of mammalian protein geranylgeranyltransferase type-I

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type

label

Structure of mammalian protein geranylgeranyltransferase type-I

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Structure of mammalian protein geranylgeranyltransferase type-I

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Structure of mammalian protein geranylgeranyltransferase type-I

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Structure of mammalian protein geranylgeranyltransferase type-I

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Structure of mammalian protein geranylgeranyltransferase type-I

@en

Structure of mammalian protein geranylgeranyltransferase type-I

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P1433

The EMBO Journal

P1476

Structure of mammalian protein geranylgeranyltransferase type-I

@en

P2093

Jeffrey S Taylor

http://www.w3.org/2001/XMLSchema#string

Kimberly L Terry

http://www.w3.org/2001/XMLSchema#string

Lorena S Beese

http://www.w3.org/2001/XMLSchema#string

Patrick J Casey

http://www.w3.org/2001/XMLSchema#string

T Scott Reid

http://www.w3.org/2001/XMLSchema#string

P2860

The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics

Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes

Influence of metal ions on substrate binding and catalytic activity of mammalian protein geranylgeranyltransferase type-I

Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

The basis for K-Ras4B binding specificity to protein farnesyltransferase revealed by 2 A resolution ternary complex structures

Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

Crystal structure of Rab geranylgeranyltransferase at 2.0 A resolution

Reaction path of protein farnesyltransferase at atomic resolution

Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution

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5963-74

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10.1093/EMBOJ/CDG571

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22

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22

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9015525

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14609943

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protein structure

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275430

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