A novel bispecific ligand-directed toxin designed to simultaneously target EGFR on human glioblastoma cells and uPAR on tumor neovasculature.
about
Targeting tumor-initiating cancer cells with dCD133KDEL shows impressive tumor reductions in a xenotransplant model of human head and neck cancerTherapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations.Targeted toxins for glioblastoma multiforme: pre-clinical studies and clinical implementation.Mutagenic Deimmunization of Diphtheria Toxin for Use in Biologic Drug Development.Bispecific targeting of EGFR and uPAR in a mouse model of head and neck squamous cell carcinoma.Targeting CD133 in an in vivo ovarian cancer model reduces ovarian cancer progression.A dual-targeting triplebody mediates preferential redirected lysis of antigen double-positive over single-positive leukemic cells.Hemangiosarcoma and its cancer stem cell subpopulation are effectively killed by a toxin targeted through epidermal growth factor and urokinase receptors.Dual targeting strategies with bispecific antibodies.Antibody-drug conjugates in glioblastoma therapy: the right drugs to the right cells.A bispecific EpCAM/CD133-targeted toxin is effective against carcinomaSafe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR.Intracerebral infusion of the bispecific targeted toxin DTATEGF in a mouse xenograft model of a human metastatic non-small cell lung cancer.Recombinant Immunotoxin Therapy of Glioblastoma: Smart Design, Key Findings, and Specific Challenges.Targeting pediatric sarcoma with a bispecific ligand immunotoxin targeting urokinase and epidermal growth factor receptors.Prolonged survival in secondary glioblastoma following local injection of targeted alpha therapy with 213Bi-substance P analogue.Targeting EGFR and uPAR on human rhabdomyosarcoma, osteosarcoma, and ovarian adenocarcinoma with a bispecific ligand-directed toxin
P2860
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P2860
A novel bispecific ligand-directed toxin designed to simultaneously target EGFR on human glioblastoma cells and uPAR on tumor neovasculature.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@ast
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@en
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@nl
type
label
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@ast
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@en
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@nl
prefLabel
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@ast
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@en
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@nl
P2093
P2860
P1476
A novel bispecific ligand-dire ...... uPAR on tumor neovasculature.
@en
P2093
Alexander K Tsai
Daniel A Vallera
John R Ohlfest
Seunguk Oh
Yanqun Shu
P2860
P2888
P304
P356
10.1007/S11060-010-0392-5
P577
2010-09-10T00:00:00Z
P5875
P6179
1040317567