Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discovery
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Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese ratsReduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing β-cells.The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosisOntogeny of hepatic energy metabolism genes in mice as revealed by RNA-sequencingStearoylCoA desaturase-5: a novel regulator of neuronal cell proliferation and differentiation.How lipidomics provides new insight into drug discovery.Alteration of Gene Expression Profile in Kidney of Spontaneously Hypertensive Rats Treated with Protein Hydrolysate of Blue Mussel (Mytilus edulis) by DNA Microarray AnalysisMicrobiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient MiceLipidomic and metabolic changes in the P4-type ATPase ATP10D deficient C57BL/6J wild type mice upon rescue of ATP10D function.The oil spill in ageing Bruch membrane.Stearoyl-CoA desaturase enzyme 1 inhibition reduces glucose utilization for de novo fatty acid synthesis and cell proliferation in 3T3-L1 adipocytes.Fenretinide induces ubiquitin-dependent proteasomal degradation of stearoyl-CoA desaturase in human retinal pigment epithelial cells.Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer.A decade of the human genome sequence--how does the medicinal chemist benefit?Stearoyl CoA desaturase 1: role in cellular inflammation and stressThe role of stearoyl-CoA desaturase in obesity, insulin resistance, and inflammation.Latest research and development trends in non-insulin anti-diabetics.An overview of patented small molecule stearoyl coenzyme-A desaturase inhibitors (2009 - 2013).Lipid droplets and liver disease: from basic biology to clinical implications.Genistein downregulates de novo lipid synthesis and impairs cell proliferation in human lung cancer cells.De novo fatty acid biosynthesis and elongation in very long-chain acyl-CoA dehydrogenase-deficient mice supplemented with odd or even medium-chain fatty acids.Prostate cancer gene expression signature of patients with high body mass index.Cloning, expression pattern analysis, and subcellular localization of Capra hircus SCD1 gene with production of transgenic mice.Liver X receptor activation increases hepatic fatty acid desaturation by the induction of SCD1 expression through an LXRα-SREBP1c-dependent mechanism.Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases.Primary Culture of Human Cumulus Cells Requires Stearoyl-Coenzyme A Desaturase 1 Activity for Steroidogenesis and Enhancing Oocyte In Vitro Maturation.Clinical determinants and mortality predictability of stearoyl-CoA desaturase-1 activity indices in dialysis patients.Sterculic oil, a natural inhibitor of SCD1, improves the metabolic state of obese OLETF rats.Updating the lipids hypothesis of inflammation and vascular disease in patients with chronic kidney disease: a stearoyl-CoA desaturase affair?
P2860
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P2860
Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discovery
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@ast
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@en
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@nl
type
label
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@ast
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@en
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@nl
prefLabel
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@ast
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@en
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@nl
P2860
P1476
Stearoyl-coenzyme A desaturase ...... ions for future drug discovery
@en
P2093
J Mark Brown
Lawrence L Rudel
P2860
P304
P356
10.1097/MOL.0B013E32833854AC
P577
2010-06-01T00:00:00Z