CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice - Wikidata - wikimedia - TriplyDB

CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice

CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice

http://www.wikidata.org/entity/Q34997923

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The association of the activation-inducible tumor necrosis factor receptor and ligand with lumbar disc herniation Defects in Germinal Center Selection in SLE 4-1BB Agonists: Multi-Potent Potentiators of Tumor Immunity CD137 and CD137L signals are main drivers of type 1, cell-mediated immune responses Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice Therapeutic potential of anti-CD137 (4-1BB) monoclonal antibodies.Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration Adjuvantive effects of anti-4-1BB agonist Ab and 4-1BBL DNA for a HIV-1 Gag DNA vaccine: different effects on cellular and humoral immunity.CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells.The role of herpesvirus entry mediator as a negative regulator of T cell-mediated responses.MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets.Agonistic Anti-CD137 Monoclonal Antibody Treatment Induces CD11bGr-1 Myeloid-derived Suppressor Cells.4-1BB (CD137), an inducible costimulatory receptor, as a specific target for cancer therapy CD137-mediated immunotherapy for allergic asthma Immune checkpoint receptors in regulating immune reactivity in rheumatic disease.Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation.Links between type I interferons and the genetic basis of disease in mouse lupus.CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent.Theory, targets and therapy in systemic lupus erythematosus.Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice.Amelioration of Japanese encephalitis by blockage of 4-1BB signaling is coupled to divergent enhancement of type I/II IFN responses and Ly-6C(hi) monocyte differentiation.Modification of accessory molecule signaling.Dual immunoregulatory pathways of 4-1BB signaling.Fc-dependent expression of CD137 on human NK cells: insights into "agonistic" effects of anti-CD137 monoclonal antibodies Immune regulation and control of regulatory T cells by OX40 and 4-1BB The IL-10 and IFN-gamma pathways are essential to the potent immunosuppressive activity of cultured CD8+ NKT-like cells Co-stimulatory and Co-inhibitory Pathways in Autoimmunity.The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses Advances in targeting cell surface signalling molecules for immune modulation Targeting of the immune system in systemic lupus erythematosus.Costimulatory pathways: physiology and potential therapeutic manipulation in systemic lupus erythematosus.T-cell costimulation and coinhibition in atherosclerosis.IFN-gamma-indoleamine-2,3 dioxygenase acts as a major suppressive factor in 4-1BB-mediated immune suppression in vivo IFNα Inducible Models of Murine SLE.Hypercostimulation through 4-1BB distorts homeostasis of immune cells.Imbalance between endothelial damage and repair: a gateway to cardiovascular disease in systemic lupus erythematosus.Intervention with costimulatory pathways as a therapeutic approach for graft-versus-host disease.

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CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice

http://www.wikidata.org/entity/Q34997923

description

2003 nî lūn-bûn

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2003 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2003 թվականի մայիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

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CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

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CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

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CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

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CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

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CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

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CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

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CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

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CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

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Journal of Clinical Investigation

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CD137 costimulatory T cell rec ...... lupus-prone NZB x NZW F1 mice

@en

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Abhijit S Bapat

http://www.w3.org/2001/XMLSchema#string

Carolyn Suwyn

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Juergen Foell

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Megan M McCausland

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Michael Haber

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Michael K Hoffmann

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Nicholas Chiorazzi

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Praveen N Chander

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Robert S Mittler

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Shawn P O'Neil

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P2860

Cutting edge: Expression of functional CD137 receptor by dendritic cells

Characterization of human homologue of 4-1BB and its ligand

Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor

The molecular basis of X-linked agammaglobulinemia, hyper-IgM syndrome, and severe combined immunodeficiency in humans.

Delineating the genetic basis of systemic lupus erythematosus.

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange

An ultrastructural study of spontaneous lupus nephritis in the NZB-BL-NZW mouse

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions.

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1505-1518

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scholarly article

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10.1172/JCI200317662

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10

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111

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12750400

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155050

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