Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus.
about
Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategiesPathogenesis of Lassa feverReporter-Expressing, Replicating-Competent Recombinant ArenavirusesNucleocapsid proteins: roles beyond viral RNA packagingAdvanced vaccine candidates for Lassa feverSevere hemorrhagic fever in strain 13/N guinea pigs infected with Lujo virusType I interferon programs innate myeloid dynamics and gene expression in the virally infected nervous systemCap binding and immune evasion revealed by Lassa nucleoprotein structureStructure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppressionCrystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA bindingStructures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune SuppressionStructure of the LCMV nucleoprotein provides a template for understanding arenavirus replication and immunosuppressionInhibition of Innate Immune Responses Is Key to Pathogenesis by ArenavirusesInfection of type I interferon receptor-deficient mice with various old world arenaviruses: a model for studying virulence and host species barriers.Differential contributions of tacaribe arenavirus nucleoprotein N-terminal and C-terminal residues to nucleocapsid functional activity.Hiding the evidence: two strategies for innate immune evasion by hemorrhagic fever viruses.Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses.Junín virus infection activates the type I interferon pathway in a RIG-I-dependent mannerPathogenesis of arenavirus hemorrhagic fevers.Arenavirus variations due to host-specific adaptation.Identification of two functional domains within the arenavirus nucleoproteinIsolation of Tacaribe virus, a Caribbean arenavirus, from host-seeking Amblyomma americanum ticks in Florida.Negative regulation of type I IFN expression by OASL1 permits chronic viral infection and CD8⁺ T-cell exhaustion.Genomic profiling of host responses to Lassa virus: therapeutic potential from primate to manDevelopment of live-attenuated arenavirus vaccines based on codon deoptimizationCross-species analysis of the replication complex of Old World arenaviruses reveals two nucleoprotein sites involved in L protein functionSingle nucleoprotein residue modulates arenavirus replication complex formation.The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever.Highly Pathogenic New World and Old World Human Arenaviruses Induce Distinct Interferon Responses in Human Cells.Lymphocytic Choriomeningitis Virus Differentially Affects the Virus-Induced Type I Interferon Response and Mitochondrial Apoptosis Mediated by RIG-I/MAVS.Self-association of lymphocytic choriomeningitis virus nucleoprotein is mediated by its N-terminal region and is not required for its anti-interferon functionD471G mutation in LCMV-NP affects its ability to self-associate and results in a dominant negative effect in viral RNA synthesisIdentification of critical amino acids within the nucleoprotein of Tacaribe virus important for anti-interferon activity.Innate immune response to arenaviral infection: a focus on the highly pathogenic New World hemorrhagic arenaviruses.Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever.Reverse Genetics Approaches to Control Arenavirus.Development of live-attenuated arenavirus vaccines based on codon deoptimization of the viral glycoprotein.Genetic variation in vitro and in vivo of an attenuated Lassa vaccine candidate.Viral tricks to grid-lock the type I interferon system.Inhibition of the type I interferon antiviral response during arenavirus infection.
P2860
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P2860
Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification of amino acid r ...... ocytic choriomeningitis virus.
@ast
Identification of amino acid r ...... ocytic choriomeningitis virus.
@en
Identification of amino acid r ...... ocytic choriomeningitis virus.
@nl
type
label
Identification of amino acid r ...... ocytic choriomeningitis virus.
@ast
Identification of amino acid r ...... ocytic choriomeningitis virus.
@en
Identification of amino acid r ...... ocytic choriomeningitis virus.
@nl
prefLabel
Identification of amino acid r ...... ocytic choriomeningitis virus.
@ast
Identification of amino acid r ...... ocytic choriomeningitis virus.
@en
Identification of amino acid r ...... ocytic choriomeningitis virus.
@nl
P2093
P2860
P356
P1433
P1476
Identification of amino acid r ...... ocytic choriomeningitis virus.
@en
P2093
Beatrice Cubitt
Juan C de la Torre
Panagiotis Giannakas
Sébastien Emonet
P2860
P304
11330-11340
P356
10.1128/JVI.00763-09
P407
P577
2009-08-26T00:00:00Z