Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a.
about
Feedback between p21 and reactive oxygen production is necessary for cell senescenceDNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilizationGadd45 in the response of hematopoietic cells to genotoxic stressGadd45 stress sensors in malignancy and leukemiaGADD45 proteins: central players in tumorigenesisThe crystal structure and dimerization interface of GADD45γCrystal structure of human Gadd45γ [corrected] reveals an active dimerGadd45g regulates dental epithelial cell proliferation through p38 MAPK-mediated p21 expressionGadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascadesCellular iron depletion and the mechanisms involved in the iron-dependent regulation of the growth arrest and DNA damage family of genesGenetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closureSelective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression.Gadd45 proteins induce G2/M arrest and modulate apoptosis in kidney cells exposed to hyperosmotic stress.Retinoblastoma loss modulates DNA damage response favoring tumor progressionAkt1 deletion prevents lung tumorigenesis by mutant K-ras.Molecular mechanisms of luteolin-7-O-glucoside-induced growth inhibition on human liver cancer cells: G2/M cell cycle arrest and caspase-independent apoptotic signaling pathways.Gadd45b mediates Fas-induced apoptosis by enhancing the interaction between p38 and retinoblastoma tumor suppressorGadd45 proteins: relevance to aging, longevity and age-related pathologies.The essence of senescence.Emerging roles of the p38 MAPK and PI3K/AKT/mTOR pathways in oncogene-induced senescence.Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesisp38 MAPK regulates the expression of ether à go-go potassium channel in human osteosarcoma cells.Stress signaling in cancer.p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells.Activating PTPN11 mutants promote hematopoietic progenitor cell-cycle progression and survival.Anti-tumor activity of N-thiolated beta-lactam antibiotics.Oncogene-induced senescence: an essential role for Runx.Gadd45b deficiency promotes premature senescence and skin aging.Non-classical p38 map kinase functions: cell cycle checkpoints and survival.Role of p38 MAP Kinase Signal Transduction in Solid TumorsGADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.Regulatory role of G9a and LSD1 in the Transcription of Olfactory Receptors during Leukaemia Cell Differentiation.Deconstructing p53 transcriptional networks in tumor suppression.Posttranscriptional regulation of gene expression-adding another layer of complexity to the DNA damage response.GADD45 proteins: roles in cellular senescence and tumor development.Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation.New role and molecular mechanism of Gadd45a in hepatic fibrosis.A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs.GADD45α is involved in the apoptosis of lymphocytes induced by riboflavin and ultraviolet light.ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence.
P2860
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P2860
Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Loss of oncogenic H-ras-induce ...... tion by disruption of Gadd45a.
@ast
Loss of oncogenic H-ras-induce ...... tion by disruption of Gadd45a.
@en
type
label
Loss of oncogenic H-ras-induce ...... tion by disruption of Gadd45a.
@ast
Loss of oncogenic H-ras-induce ...... tion by disruption of Gadd45a.
@en
prefLabel
Loss of oncogenic H-ras-induce ...... tion by disruption of Gadd45a.
@ast
Loss of oncogenic H-ras-induce ...... tion by disruption of Gadd45a.
@en
P2093
P2860
P1476
Loss of oncogenic H-ras-induce ...... tion by disruption of Gadd45a.
@en
P2093
Dmitry V Bulavin
M Christine Hollander
Oleg Kovalsky
P2860
P304
P356
10.1128/MCB.23.11.3859-3871.2003
P407
P577
2003-06-01T00:00:00Z