Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding.
about
Nucleolin links to arsenic-induced stabilization of GADD5alpha mRNAInterferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytesNF-kappa B-mediated repression of growth arrest- and DNA-damage-inducible proteins 45alpha and gamma is essential for cancer cell survivalGADD45 proteins: central players in tumorigenesisActivation of MTK1/MEKK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domainJNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsTranscriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptationThe crystal structure and dimerization interface of GADD45γActin recovery and bud emergence in osmotically stressed cells requires the conserved actin interacting mitogen-activated protein kinase kinase kinase Ssk2p/MTK1 and the scaffold protein Spa2pIdentification of a gadd45beta 3' enhancer that mediates SMAD3- and SMAD4-dependent transcriptional induction by transforming growth factor betaAxin utilizes distinct regions for competitive MEKK1 and MEKK4 binding and JNK activationZebrafish GADD45beta genes are involved in somite segmentationGadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascadesGADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytesCytokine-regulated GADD45G induces differentiation and lineage selection in hematopoietic stem cells.Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy.Gadd45b mediates Fas-induced apoptosis by enhancing the interaction between p38 and retinoblastoma tumor suppressorAblation of MEKK4 kinase activity causes neurulation and skeletal patterning defects in the mouse embryo.Hepatocyte proliferation/growth arrest balance in the liver of mice during E. multilocularis infection: a coordinated 3-stage course.Critical role of the JNK-p53-GADD45α apoptotic cascade in mediating oxidative cytotoxicity in hippocampal neurons.Pregnane X receptor PXR activates the GADD45beta gene, eliciting the p38 MAPK signal and cell migration.Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a.Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27MicroRNA-383 regulates the apoptosis of tumor cells through targeting Gadd45g.Reduced levels of ATF-2 predispose mice to mammary tumors.Expression of the Drosophila melanogaster GADD45 homolog (CG11086) affects egg asymmetric development that is mediated by the c-Jun N-terminal kinase pathway.The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells.Regulation of DLK-1 kinase activity by calcium-mediated dissociation from an inhibitory isoformPhosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy.Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells.Response regulator-mediated MAPKKK heteromer promotes stress signaling to the Spc1 MAPK in fission yeast.Anti-tumor activity of N-thiolated beta-lactam antibiotics.Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4HER2/HER3 regulates extracellular acidification and cell migration through MTK1 (MEKK4).Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination.A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiationNF-kappaB signaling: multiple angles to target OA.Response to hyperosmotic stressPXR cross-talks with internal and external signals in physiological and pathophysiological responses.Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation.
P2860
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P2860
Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Regulation of MTK1/MEKK4 kinas ...... tory domain and GADD45 binding
@nl
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@ast
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@en
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@en-gb
type
label
Regulation of MTK1/MEKK4 kinas ...... tory domain and GADD45 binding
@nl
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@ast
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@en
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@en-gb
prefLabel
Regulation of MTK1/MEKK4 kinas ...... tory domain and GADD45 binding
@nl
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@ast
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@en
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@en-gb
P2093
P2860
P3181
P1476
Regulation of MTK1/MEKK4 kinas ...... ory domain and GADD45 binding.
@en
P2093
Elizabeth A Witten
Haruo Saito
Hiroaki Mita
Junichiro Tsutsui
Mutsuhiro Takekawa
P2860
P304
P3181
P356
10.1128/MCB.22.13.4544-4555.2002
P407
P577
2002-07-01T00:00:00Z