Neuropathy target esterase is required for adult vertebrate axon maintenance
about
Spg20-/- mice reveal multimodal functions for Troyer syndrome protein spartin in lipid droplet maintenance, cytokinesis and BMP signalingOrganophosphate-induced changes in the PKA regulatory function of Swiss Cheese/NTE lead to behavioral deficits and neurodegenerationCompound heterozygous PNPLA6 mutations cause Boucher-Neuhäuser syndrome with late-onset ataxia.Motor neuron disease due to neuropathy target esterase mutation: enzyme analysis of fibroblasts from human subjects yields insights into pathogenesis.Constructs of human neuropathy target esterase catalytic domain containing mutations related to motor neuron disease have altered enzymatic properties.Mutations in PNPLA6 are linked to photoreceptor degeneration and various forms of childhood blindness.Calcium-independent phospholipases A2 and their roles in biological processes and diseases.Phosphatidylcholine and the CDP-choline cycle.Knockdown of Pnpla6 protein results in motor neuron defects in zebrafish.Identifying safer anti-wear triaryl phosphate additives for jet engine lubricants.CREB is required for cAMP/PKA signals upregulating neuropathy target esterase expression.Neurodegeneration in a Drosophila model of adrenoleukodystrophy: the roles of the Bubblegum and Double bubble acyl-CoA synthetases.Disturbed phospholipid homeostasis in endoplasmic reticulum initiates tri-o-cresyl phosphate-induced delayed neurotoxicityHereditary spastic paraplegias: membrane traffic and the motor pathway.Cellular pathways of hereditary spastic paraplegia.Neuropathy target esterase impairments cause Oliver-McFarlane and Laurence-Moon syndromes.Organophosphate neurotoxicity to the voluntary motor system on the trail of environment-caused amyotrophic lateral sclerosis: the known, the misknown, and the unknown.Neuropathy target esterase in mouse whole blood as a biomarker of exposure to neuropathic organophosphorus compounds.The phospholipase PNPLA7 functions as a lysophosphatidylcholine hydrolase and interacts with lipid droplets through its catalytic domain.NTE/PNPLA6 is expressed in mature Schwann cells and is required for glial ensheathment of Remak fibers.Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.Kinetic interactions of a neuropathy potentiator (phenylmethylsulfonyl fluoride) with the neuropathy target esterase and other membrane bound esterases.From yeast to humans - roles of the Kennedy pathway for phosphatidylcholine synthesis.Functional pathways altered after silencing Pnpla6 (the codifying gene of neuropathy target esterase) in mouse embryonic stem cells under differentiation.The destruction box is involved in the degradation of the NTE family proteins by the proteasome.Analysis of the neurotoxic effects of neuropathic organophosphorus compounds in adult zebrafish.Activation of Neuregulin 1/ErbB Signaling Is Involved in the Development of TOCP-Induced Delayed Neuropathy.
P2860
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P2860
Neuropathy target esterase is required for adult vertebrate axon maintenance
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Neuropathy target esterase is required for adult vertebrate axon maintenance
@ast
Neuropathy target esterase is required for adult vertebrate axon maintenance
@en
type
label
Neuropathy target esterase is required for adult vertebrate axon maintenance
@ast
Neuropathy target esterase is required for adult vertebrate axon maintenance
@en
prefLabel
Neuropathy target esterase is required for adult vertebrate axon maintenance
@ast
Neuropathy target esterase is required for adult vertebrate axon maintenance
@en
P2093
P2860
P1476
Neuropathy target esterase is required for adult vertebrate axon maintenance
@en
P2093
David J Read
John B Cavanagh
Paul Glynn
P2860
P304
11594-11600
P356
10.1523/JNEUROSCI.3007-09.2009
P407
P577
2009-09-01T00:00:00Z