Structural aspects and design of low-molecular-mass complement inhibitors.

Structural aspects and design of low-molecular-mass complement inhibitors.

Item
http://www.wikidata.org/entity/Q35003513
Compstatin: a complement inhibitor on its way to clinical applicationDesign of a modified mouse protein with ligand binding properties of its human analog by molecular dynamics simulations: the case of C3 inhibition by compstatinNew compstatin variants through two de novo protein design frameworks.Complement-mediated inhibition of neovascularization reveals a point of convergence between innate immunity and angiogenesis.Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency.Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke.Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells.A new generation of potent complement inhibitors of the Compstatin family.New compstatin peptides containing N-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristicsSpecies specificity of the complement inhibitor compstatin investigated by all-atom molecular dynamics simulationsMolecular dynamics in drug design: new generations of compstatin analogs.Development of complement therapeutics for inhibition of immune-mediated red cell destructionThe proinflammatory mediators C3a and C5a are essential for liver regenerationPeptide redesign for inhibition of the complement system: Targeting age-related macular degeneration.Recent developments in low molecular weight complement inhibitorsNovel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures.
P2860

Structural aspects and design of low-molecular-mass complement inhibitors.

Item
http://www.wikidata.org/entity/Q35003513
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Structural aspects and design of low-molecular-mass complement inhibitors.
@ast
Structural aspects and design of low-molecular-mass complement inhibitors.
@en
type
label
Structural aspects and design of low-molecular-mass complement inhibitors.
@ast
Structural aspects and design of low-molecular-mass complement inhibitors.
@en
prefLabel
Structural aspects and design of low-molecular-mass complement inhibitors.
@ast
Structural aspects and design of low-molecular-mass complement inhibitors.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Structural aspects and design of low-molecular-mass complement inhibitors.
@en
P2093
P304
P31
P356
P433
P478
P577
P698
P921