DNA-templated homo- and heterodimerization of peptide nucleic acid encoded oligosaccharides that mimick the carbohydrate epitope of HIV.
about
Recent strategies targeting HIV glycans in vaccine designDNA display of glycoconjugates to emulate oligomeric interactions of glycansA LecA ligand identified from a galactoside-conjugate array inhibits host cell invasion by Pseudomonas aeruginosaInteraction-dependent PCR: identification of ligand-target pairs from libraries of ligands and libraries of targets in a single solution-phase experiment.Effects of neighboring glycans on antibody-carbohydrate interaction.Selection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells.Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds.Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries.DNA display of PNA-tagged ligands: a versatile strategy to screen libraries and control geometry of multidentate ligandsExpanding the scope of PNA-encoded synthesis (PES): Mtt-protected PNA fully orthogonal to fmoc chemistry and a broad array of robust diversity-generating reactions.Directed evolution of multivalent glycopeptides tightly recognized by HIV antibody 2G12.PNA-encoded synthesis (PES) of a 10 000-member hetero-glycoconjugate library and microarray analysis of diverse lectins.Automated screening for small organic ligands using DNA-encoded chemical libraries.Glycomaterials for probing host-pathogen interactions and the immune response.Glycopolymer probes of signal transductionSelf-assembled antibody multimers through peptide nucleic acid conjugation.DNA-guided display of proteins and protein ligands for the interrogation of biology.Multivalency as a chemical organization and action principle.Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications.Bridging lectin binding sites by multivalent carbohydrates.Carbohydrate-PNA and aptamer-PNA conjugates for the spatial screening of lectins and lectin assemblies.DNA as a molecular ruler: interrogation of a tandem SH2 domain with self-assembled, bivalent DNA-peptide complexes.High temperature SELMA: evolution of DNA-supported oligomannose clusters which are tightly recognized by HIV bnAb 2G12.Nanoscale materials for probing the biological functions of the glycocalyx.Oligonucleotide-Based Mimetics of Hepatocyte Growth Factor.A stable bidentate protein binder achieved via DNA self-assembly driven ligand migration.Probing heterobivalent binding to the endocytic AP-2 adaptor complex by DNA-based spatial screening.Synthesis of a polymerizable, bivalent glycan mimetic of the HIV envelope spike gp120.Design, preparation, and selection of DNA-encoded dynamic librariesInterface Immobilization Chemistry of cRGD-based Peptides Regulates Integrin Mediated Cell Adhesion.Directed evolution of 2G12-targeted nonamannose glycoclusters by SELMA.Carbohydrate microarrays.DNA-Encoded Chemical Libraries: A Selection System Based On Endowing Organic Compounds with Amplifiable Information.Dynamic Cooperative Glycan Assembly Blocks the Binding of Bacterial Lectins to Epithelial Cells.Rapid assembly of branched mannose oligosaccharides through consecutive regioselective glycosylation: A convergent and efficient strategy.Photoaffinity labeling of small-molecule-binding proteins by DNA-templated chemistry.DNA-encoded chemical libraries: Achievements and remaining challenges.DNA-controlled bivalent presentation of ligands for the estrogen receptor.Picture perfect: DNA-templated photoaffinity labeling.DNA glycoclusters and DNA-based carbohydrate microarrays: From design to applications
P2860
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P2860
DNA-templated homo- and heterodimerization of peptide nucleic acid encoded oligosaccharides that mimick the carbohydrate epitope of HIV.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
DNA-templated homo- and hetero ...... e carbohydrate epitope of HIV.
@ast
DNA-templated homo- and hetero ...... e carbohydrate epitope of HIV.
@en
type
label
DNA-templated homo- and hetero ...... e carbohydrate epitope of HIV.
@ast
DNA-templated homo- and hetero ...... e carbohydrate epitope of HIV.
@en
prefLabel
DNA-templated homo- and hetero ...... e carbohydrate epitope of HIV.
@ast
DNA-templated homo- and hetero ...... e carbohydrate epitope of HIV.
@en
P2093
P356
P1476
DNA-templated homo- and hetero ...... he carbohydrate epitope of HIV
@en
P2093
Katarzyna Gorska
Kuo-Ting Huang
Olivier Chaloin
P304
P356
10.1002/ANIE.200903328
P407
P577
2009-01-01T00:00:00Z