Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides.
about
Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperaturesStructure-based prediction of asparagine and aspartate degradation sites in antibody variable regionsAnalysis of Monoclonal Antibody Sequence and Post-translational Modifications by Time-controlled Proteolysis and Tandem Mass Spectrometry.Pepsin-Containing Membranes for Controlled Monoclonal Antibody Digestion Prior to Mass Spectrometry Analysis.Lens β-crystallins: the role of deamidation and related modifications in aging and cataract.Large-scale analysis of post-translational modifications in E. coli under glucose-limiting conditions.Tissue transglutaminase-mediated glutamine deamidation of beta-amyloid peptide increases peptide solubility, whereas enzymatic cross-linking and peptide fragmentation may serve as molecular triggers for rapid peptide aggregationData analysis strategy for maximizing high-confidence protein identifications in complex proteomes such as human tumor secretomes and human serumTop-down study of β2-microglobulin deamidationA universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies.Mass spectrometric peptide analysis of 2DE-separated mouse spinal cord and rat hippocampus proteins suggests an NGxG motif of importance for in vivo deamidation.A new strategy to stabilize oxytocin in aqueous solutions: I. The effects of divalent metal ions and citrate buffer.Pitfalls in protein quantitation using acid-catalyzed O18 labeling: hydrolysis-driven deamidation.The predatory bacterium Bdellovibrio bacteriovorus aspartyl-tRNA synthetase recognizes tRNAAsn as a substrate.Large-Scale Targeted Proteomics Using Internal Standard Triggered-Parallel Reaction Monitoring (IS-PRM).Characterization of Pharmaceutical IgG and Biosimilars Using Miniaturized Platforms and LC-MS/MS.Quality assessment of U.S. marketplace vancomycin for injection products using high-resolution liquid chromatography-mass spectrometry and potency assays.Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS.Determination of Histidine pKa Values in the Propeptides of Furin and Proprotein Convertase 1/3 Using Histidine Hydrogen-Deuterium Exchange Mass Spectrometry.Brain proteomics supports the role of glutamate metabolism and suggests other metabolic alterations in protein l-isoaspartyl methyltransferase (PIMT)-knockout miceThe role for neutrophil extracellular traps in cystic fibrosis autoimmunity.Mechanisms of glucagon degradation at alkaline pH.Tailoring recombinant protein quality by rational media design.Quantification of biopharmaceuticals and biomarkers in complex biological matrices: a comparison of liquid chromatography coupled to tandem mass spectrometry and ligand binding assays.Assessment of chemical modifications of sites in the CDRs of recombinant antibodies: Susceptibility vs. functionality of critical quality attributes.Relative Quantification of Sites of Peptide and Protein Modification Using Size Exclusion Chromatography Coupled with Electron Transfer Dissociation.Ion coalescence in Fourier transform mass spectrometry: should we worry about this in shotgun proteomics?Structural Characterisation of Non-Deamidated Acidic Variants of Erwinia chrysanthemi L-asparaginase Using Small-Angle X-ray Scattering and Ion-Mobility Mass Spectrometry.The Separation and Quantitation of Peptides with and without Oxidation of Methionine and Deamidation of Asparagine Using Hydrophilic Interaction Liquid Chromatography with Mass Spectrometry (HILIC-MS).Analysis of isoaspartic Acid by selective proteolysis with Asp-N and electron transfer dissociation mass spectrometry.An Arabidopsis ATP-dependent, DEAD-box RNA helicase loses activity upon IsoAsp formation but is restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE.Sequence and Solution Effects on the Prevalence of d-Isomers Produced by Deamidation.Chagas disease vector blood meal sources identified by protein mass spectrometry.Development of SI-traceable C-peptide certified reference material NMIJ CRM 6901-a using isotope-dilution mass spectrometry-based amino acid analyses.Post-Translational Modifications of Protein Backbones: Unique Functions, Mechanisms, and Challenges.Strategies for analysis of isomeric peptides.Dual universal peptide approach to bioanalysis of human monoclonal antibody protein drug candidates in animal studies.Quantification of in vivo site-specific Asp isomerization and Asn deamidation of mAbs in animal serum using IP-LC-MS.Assessment of susceptible chemical modification sites of trastuzumab and endogenous human immunoglobulins at physiological conditionsMolecular diversity and function of jasmintides from Jasminum sambac
P2860
Q28478926-1B598D78-B5DC-4680-B70E-16CC7098D62DQ28539968-B5B4A0E3-5C1A-4962-B28A-5B4370DEFD1FQ30277986-33697287-2190-4377-A3E2-2753BF4C18BCQ30278544-3B2365C9-574B-4A3F-A203-D6856B9662F0Q30360031-A9F86CAE-F188-4942-BB49-8C9E19D6B664Q33568235-ADE4B090-8BCD-4D90-83E2-315798AF7FD3Q33814180-16726143-0AE0-485D-8803-2E60016E704AQ34033839-2EE95376-5B58-4962-91D4-434EFD4943F8Q34219743-D0746437-8246-483E-A930-3C17BB45EF3EQ34279551-55FC65D1-427C-4620-8F2C-21120FAEA06FQ34628096-B24F09FD-1F32-4D75-BAB4-52A5E287BEB6Q34901001-C5C99874-B4BB-4513-B1DE-B241114A03FAQ35214327-A9C7C95F-00BD-4E86-A3EF-D338F43A30DAQ35358515-7F16B04D-F3BC-4E8C-8C11-E9F9BC935975Q35692132-CA04980B-8173-43E2-AF01-E2CB38F130C6Q35975965-89E748EA-B6C5-41DD-8B72-AFDE04A0FD33Q36018817-A8D3DC83-5F61-4F25-B1C1-F00A80B4ED67Q36399003-AC9DAF48-F510-4F6A-BA74-5BF78A168302Q36994909-6D470E72-B514-4BE5-AD52-87B390AB6819Q37282869-1CEBAF80-B3CC-4086-80D2-ACCDC9A1FB45Q37351609-A0AB7CB2-28C0-400E-AAB0-0DD834B3040FQ37626914-D1B4EC4B-04EC-440B-8479-8E20F1B143B9Q38416739-13F94A77-C603-457F-B9D2-39C47290442BQ38500988-0360DDAF-11C5-4B73-81C1-3E62046FB406Q38717942-BAD2E07D-4D1F-469A-AC81-D9A94EF7A8C2Q39852863-D600493E-CB6B-48F2-A712-EE6BB896BF8CQ40606845-E5839F2B-CA76-4674-8832-B142B7AD8EB9Q40872220-9E3D28F1-5CBE-4F12-BDF5-8AE0B6E87C68Q41692568-BCBE85D0-BE3D-4D77-BB92-192C0C6EBC43Q41970463-9A5272BC-91E8-457D-AF16-5D9C8608551CQ45739160-6E60B9DB-0AAB-49CE-B05F-8BC5CB264252Q45969140-F22DA409-F42E-49E0-8E49-785F8CD8AB40Q46242941-7771561F-3CF8-4A48-B69E-BA2EF5BE1720Q46350298-BED07A54-E856-493D-B0F7-02DC0B185441Q47610623-253D698B-F270-4172-AC47-D7E5B2A02326Q47784780-194B090F-13AD-4F2D-80A1-B7A8031480A7Q50931513-14DCAE93-5859-4A92-B267-CD583B0542A3Q51651469-9A63B1F1-2709-4938-AC0C-783195122A8CQ57146442-3899FBE8-6C06-4C33-8844-ECAFC1B2329EQ57236325-1D8229F6-28B3-458F-967F-14DD70A4BA92
P2860
Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mass spectrometric analysis of ...... isomerization in polypeptides.
@ast
Mass spectrometric analysis of ...... isomerization in polypeptides.
@en
type
label
Mass spectrometric analysis of ...... isomerization in polypeptides.
@ast
Mass spectrometric analysis of ...... isomerization in polypeptides.
@en
prefLabel
Mass spectrometric analysis of ...... isomerization in polypeptides.
@ast
Mass spectrometric analysis of ...... isomerization in polypeptides.
@en
P2860
P356
P1433
P1476
Mass spectrometric analysis of ...... isomerization in polypeptides.
@en
P2093
Hongqian Yang
Roman A Zubarev
P2860
P304
P356
10.1002/ELPS.201000027
P577
2010-06-01T00:00:00Z