The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
about
Biology of adeno-associated viral vectors in the central nervous systemAdeno-associated Virus as a Mammalian DNA VectorStructural Insight into the Unique Properties of Adeno-Associated Virus Serotype 9Structural Insights into Adeno-Associated Virus Serotype 5Heart failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodelingIntranasal antibody gene transfer in mice and ferrets elicits broad protection against pandemic influenza.Sialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage diseaseWhole body correction of mucopolysaccharidosis IIIA by intracerebrospinal fluid gene therapyComparative analysis of adeno-associated virus capsid stability and dynamicsLong-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment.CRISPR-Cas9 knockin mice for genome editing and cancer modelingPulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways disease.Systemic gene delivery to the central nervous system using Adeno-associated virus.Biodistribution of adeno-associated virus serotype 9 (AAV9) vector after intrathecal and intravenous delivery in mouseNaturally enveloped AAV vectors for shielding neutralizing antibodies and robust gene delivery in vivo.Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport.Adeno-associated virus: fit to serveIntravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice.In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection.AAV9 targets cone photoreceptors in the nonhuman primate retina.Multiple roles for sialylated glycans in determining the cardiopulmonary tropism of adeno-associated virus 4Functional analysis of the putative integrin recognition motif on adeno-associated virus 9.Gene transfer properties and structural modeling of human stem cell-derived AAV.The expression pattern of systemically injected AAV9 in the developing mouse retina is determined by ageEffectiveness of gene delivery systems for pluripotent and differentiated cells.Controlling AAV Tropism in the Nervous System with Natural and Engineered Capsids.In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene TherapyAdvances in cell and gene-based therapies for cystic fibrosis lung diseaseSystemic gene delivery following intravenous administration of AAV9 to fetal and neonatal mice and late-gestation nonhuman primates.Identification of the galactose binding domain of the adeno-associated virus serotype 9 capsidAn acidic oligopeptide displayed on AAV2 improves axial muscle tropism after systemic delivery.Glycan binding avidity determines the systemic fate of adeno-associated virus type 9.Gene transfer in the lung using recombinant adeno-associated virusPseudotyped adeno-associated virus 2/9-delivered CCL11 shRNA alleviates lung inflammation in an allergen-sensitized mouse model.Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene TherapyWidespread Central Nervous System Gene Transfer and Silencing After Systemic Delivery of Novel AAV-AS Vector.Efficient gene delivery and selective transduction of astrocytes in the mammalian brain using viral vectors.Multiple recombinant adeno-associated viral vector serotypes display persistent in vivo gene expression in vector-transduced rat stifle joints.Postentry processing of recombinant adeno-associated virus type 1 and transduction of the ferret lung are altered by a factor in airway secretions.Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiency.
P2860
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P2860
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
@ast
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
@en
type
label
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
@ast
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
@en
prefLabel
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
@ast
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
@en
P2093
P2860
P356
P1476
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
@en
P2093
Christie L Bell
Guang-Ping Gao
Luk H Vandenberghe
Maria P Limberis
Mavis Agbandje-McKenna
Peter Bell
P2860
P304
P356
10.1172/JCI57367
P407
P577
2011-05-16T00:00:00Z