FHIT: from gene discovery to cancer treatment and prevention.
about
Widespread presence of "bacterial-like" PPP phosphatases in eukaryotesSerine, glycine and one-carbon units: cancer metabolism in full circleExpression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancerGenomic copy number alterations in clear cell renal carcinoma: associations with case characteristics and mechanisms of VHL gene inactivationActivation state-dependent interaction between Gαq subunits and the Fhit tumor suppressor.Association of activated Gαq to the tumor suppressor Fhit is enhanced by phospholipase CβChromosomal imbalances are uncommon in chagasic megaesophagus.Fhit, a tumor suppressor protein, induces autophagy via 14-3-3τ in non-small cell lung cancer cells.Loss of fragile histidine triad protein expression in inflammatory bowel disease.Identification of putative cancer genes through data integration and comparative genomics between plants and humans.Comparative analysis of algorithms for integration of copy number and expression data.Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites.Loss of FHIT expression in gastric mucosa of patients with family histories of gastric cancer and Helicobacter pylori infectionInfluence of FHIT on benzo[a]pyrene-induced tumors and alopecia in mice: chemoprevention by budesonide and N-acetylcysteine.Transcriptional profiling of the cell cycle checkpoint gene krüppel-like factor 4 reveals a global inhibitory function in macromolecular biosynthesis.Expression profiles of acute lymphoblastic and myeloblastic leukemias with ALL-1 rearrangementsFHIT-proteasome degradation caused by mitogenic stimulation of the EGF receptor family in cancer cells.Gallbladder cancer: lessons from a rare tumour.The tumor suppressor Fhit acts as a repressor of beta-catenin transcriptional activity.The expression of FHIT, PCNA and EGFR in benign and malignant breast lesionsMethylation in esophageal carcinogenesis.Identification of the HIT-45 protein from Trypanosoma brucei as an FHIT protein/dinucleoside triphosphatase: substrate specificity studies on the recombinant and endogenous proteins.Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy.Fhit tumor suppressor: guardian of the preneoplastic genome.Promoter methylation of tumor suppressor genes in esophageal squamous cell carcinoma.HPV, KRAS mutations, alcohol consumption and tobacco smoking effects on esophageal squamous-cell carcinoma carcinogenesis.CRISPR/Cas9: molecular tool for gene therapy to target genome and epigenome in the treatment of lung cancer.Fhit regulates invasion of lung tumor cells.Silencing of the tumor suppressor gene FHIT is highly characteristic for MLL gene rearranged infant acute lymphoblastic leukemia.Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.Human papillomavirus and non-small cell lung cancer.Loss of FHIT protein expression is a marker of adverse evolution in good prognosis localized breast cancer.5'-CpG island methylation of the FHIT gene is associated with reduced protein expression and higher clinical stage in cervical carcinomas.FHIT mRNA and protein expression in hepatocellular carcinoma.Contig array CGH at 3p14.2 points to the FRA3B/FHIT common fragile region as the target gene in diffuse large B-cell lymphoma.FHIT promoter DNA methylation and expression analysis in childhood acute lymphoblastic leukemia.Inverse correlation of aberrant expression of fragile histidine triad (FHIT) protein with cyclin D1 protein and prognosis in Chinese patients with cholangiocarcinoma.Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome.
P2860
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P2860
FHIT: from gene discovery to cancer treatment and prevention.
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
FHIT: from gene discovery to cancer treatment and prevention.
@ast
FHIT: from gene discovery to cancer treatment and prevention.
@en
type
label
FHIT: from gene discovery to cancer treatment and prevention.
@ast
FHIT: from gene discovery to cancer treatment and prevention.
@en
prefLabel
FHIT: from gene discovery to cancer treatment and prevention.
@ast
FHIT: from gene discovery to cancer treatment and prevention.
@en
P2093
P1433
P1476
FHIT: from gene discovery to cancer treatment and prevention.
@en
P2093
Alexey Palamarchuk
Kay Huebner
Nicola Zanesi
Yuri Pekarsky
P304
P356
10.1016/S1470-2045(02)00931-2
P577
2002-12-01T00:00:00Z