Fhit tumor suppressor: guardian of the preneoplastic genome.
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The clinicopathological significance and ethnic difference of FHIT hypermethylation in non-small-cell lung carcinoma: a meta-analysis and literature reviewReduced FHIT expression is associated with mismatch repair deficient and high CpG island methylator phenotype colorectal cancer.The roles of sphingosine kinase 1 and 2 in regulating the metabolome and survival of prostate cancer cells.Alterations of tumor-related genes do not exactly match the histopathological grade in gastric adenocarcinomas.Replicative Stress and the FHIT Gene: Roles in Tumor Suppression, Genome Stability and Prevention of Carcinogenesis.PTEN C-terminal deletion causes genomic instability and tumor development.Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples.Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains.FHIT gene expression is repressed by mitogenic signaling through the PI3K/AKT/FOXO pathway.Comparison of structural genetics of non-schistosoma-associated squamous cell carcinoma of the urinary bladder.The clinicopathological significance of FHIT hypermethylation in non-small cell lung cancer, a meta-analysis and literature review.Characterization of the role of Fhit in suppression of DNA damage.The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells.Exome-wide single-base substitutions in tissues and derived cell lines of the constitutive Fhit knockout mouse.Aberrant expression of DNA damage response proteins is associated with breast cancer subtype and clinical featuresReduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation.Recurrent R-spondin fusions in colon cancer.Fhit deficiency-induced global genome instability promotes mutation and clonal expansion.A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells.Fhit loss-associated initiation and progression of neoplasia in vitro.WWOX gene and gene product: tumor suppression through specific protein interactions.Identification of Fhit as a post-transcriptional effector of Thymidine Kinase 1 expression.The Fhit protein: an opportunity to overcome chemoresistance.A selected group of large common fragile site genes have decreased expression in oropharyngeal squamous cell carcinomas.Epigenomics and targeted therapy in cancer.Impact of FHIT loss on the translation of cancer-associated mRNAs.Fhit down-regulation is an early event in pancreatic carcinogenesis.
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Fhit tumor suppressor: guardian of the preneoplastic genome.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Fhit tumor suppressor: guardian of the preneoplastic genome.
@en
Fhit tumor suppressor: guardian of the preneoplastic genome.
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type
label
Fhit tumor suppressor: guardian of the preneoplastic genome.
@en
Fhit tumor suppressor: guardian of the preneoplastic genome.
@nl
prefLabel
Fhit tumor suppressor: guardian of the preneoplastic genome.
@en
Fhit tumor suppressor: guardian of the preneoplastic genome.
@nl
P2093
P2860
P356
P1433
P1476
Fhit tumor suppressor: guardian of the preneoplastic genome.
@en
P2093
Flavia Pichiorri
Francesco Trapasso
Hideshi Ishii
Hiroshi Okamura
Kay Huebner
Sung-Suk Suh
Tiziana Palumbo
P2860
P304
P356
10.2217/14796694.4.6.815
P407
P577
2008-12-01T00:00:00Z