Local peptide movement in the photoreaction intermediate of rhodopsin.
about
Crystal structure of a photoactivated deprotonated intermediate of rhodopsinDiversity and modularity of G protein-coupled receptor structuresNew insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptorsConstitutively active rhodopsin and retinal diseaseThe structural basis of agonist-induced activation in constitutively active rhodopsinStabilized G protein binding site in the structure of constitutively active metarhodopsin-IIRetinal conformation governs pKa of protonated Schiff base in rhodopsin activationMolecular dynamics simulations reveal specific interactions of post-translational palmitoyl modifications with rhodopsin in membranes.Activation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.Chemistry and biology of the initial steps in vision: the Friedenwald lecture.Structural waters define a functional channel mediating activation of the GPCR, rhodopsin.Showcasing modern molecular dynamics simulations of membrane proteins through G protein-coupled receptors.Molecular simulations and solid-state NMR investigate dynamical structure in rhodopsin activation.G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy.Structure-function of the G protein-coupled receptor superfamily.Retinal ligand mobility explains internal hydration and reconciles active rhodopsin structuresInternal hydration increases during activation of the G-protein-coupled receptor rhodopsin.Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening.Rhodopsin and the others: a historical perspective on structural studies of G protein-coupled receptors.Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins.Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?Retinal conformation and dynamics in activation of rhodopsin illuminated by solid-state H NMR spectroscopy.Sequential rearrangement of interhelical networks upon rhodopsin activation in membranes: the Meta II(a) conformational substate.Putative active states of a prototypic g-protein-coupled receptor from biased molecular dynamics.Complexes between photoactivated rhodopsin and transducin: progress and questions.Modern homology modeling of G-protein coupled receptors: which structural template to use?Structure and function of G protein-coupled receptors using NMR spectroscopy.Comparative analysis of the heptahelical transmembrane bundles of G protein-coupled receptors.Action of molecular switches in GPCRs--theoretical and experimental studies.Conservation of molecular interactions stabilizing bovine and mouse rhodopsin.Modelling time-resolved two-dimensional electronic spectroscopy of the primary photoisomerization event in rhodopsin.Synergy within structural biology of single crystal optical spectroscopy and X-ray crystallography.Energy landscapes as a tool to integrate GPCR structure, dynamics, and function.Location of the retinal chromophore in the activated state of rhodopsin*.Low-Temperature Trapping of Photointermediates of the Rhodopsin E181Q Mutant.Solid-state 2H NMR relaxation illuminates functional dynamics of retinal cofactor in membrane activation of rhodopsinProgress in elucidating the structural and dynamic character of G Protein-Coupled Receptor oligomers for use in drug discovery.Time-resolved WAXS reveals accelerated conformational changes in iodoretinal-substituted proteorhodopsin.The significance of G protein-coupled receptor crystallography for drug discovery.Crystallographic Study of the LUMI Intermediate of Squid Rhodopsin.
P2860
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P2860
Local peptide movement in the photoreaction intermediate of rhodopsin.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Local peptide movement in the photoreaction intermediate of rhodopsin.
@ast
Local peptide movement in the photoreaction intermediate of rhodopsin.
@en
type
label
Local peptide movement in the photoreaction intermediate of rhodopsin.
@ast
Local peptide movement in the photoreaction intermediate of rhodopsin.
@en
prefLabel
Local peptide movement in the photoreaction intermediate of rhodopsin.
@ast
Local peptide movement in the photoreaction intermediate of rhodopsin.
@en
P2860
P356
P1476
Local peptide movement in the photoreaction intermediate of rhodopsin.
@en
P2093
Hitoshi Nakamichi
Tetsuji Okada
P2860
P304
12729-12734
P356
10.1073/PNAS.0601765103
P407
P577
2006-08-14T00:00:00Z