T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters.
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Current approaches to studying membrane organizationMicro- and nanoscale engineering of cell signalingExperimental and theoretical bases for mechanisms of antigen discrimination by T cellsLeishmania spp. Proteome Data Sets: A Comprehensive Resource for Vaccine Development to Target Visceral LeishmaniasisLinking form to function: Biophysical aspects of artificial antigen presenting cell designThe actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells.Barcoding T cell calcium response diversity with methods for automated and accurate analysis of cell signals (MAAACS)Myosin IIA modulates T cell receptor transport and CasL phosphorylation during early immunological synapse formationProbing the Heterogeneity of Protein Kinase Activation in Cells by Super-resolution MicroscopyBiophysical mechanism of T-cell receptor triggering in a reconstituted systemManipulating the lateral diffusion of surface-anchored EGF demonstrates that receptor clustering modulates phosphorylation levelsSingle molecule tracking on supported membranes with arrays of optical nanoantennas.The significance of membrane fluidity of feeder cell-derived substrates for maintenance of iPS cell stemness.Molecular Occupancy of Nanodot Arrays.Size-based chromatography of signaling clusters in a living cell membraneLigand-induced homotypic and heterotypic clustering of apolipoprotein E receptor 2Meeting report--Visualizing signaling nanoplatforms at a higher spatiotemporal resolution.Molecular kinetics. Ras activation by SOS: allosteric regulation by altered fluctuation dynamics.A quantitative assessment of costimulation and phosphatase activity on microclusters in early T cell signaling.Supported membranes embedded with fixed arrays of gold nanoparticlesA Mechanical Switch Couples T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD3ζζ.Protein Conformational Changes Are Detected and Resolved Site Specifically by Second-Harmonic Generation.E-cadherin junction formation involves an active kinetic nucleation process.How much of virus-specific CD8 T cell reactivity is detected with a peptide pool when compared to individual peptides?Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells.Repeated exposure to trace amounts of woodchuck hepadnavirus induces molecularly evident infection and virus-specific T cell response in the absence of serological infection markers and hepatitisSpatial partitioning improves the reliability of biochemical signalingDNA-mediated assembly of protein heterodimers on membrane surfaces.Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cellsSignaling clusters in the cell membrane.Characterization and optimization of the glucan particle-based vaccine platform.T cell activation is determined by the number of presented antigens.Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.Receptor signaling clusters in the immune synapse.New insights into the T cell synapse from single molecule techniques.Structural and biophysical determinants of αβ T-cell antigen recognition.How the TCR balances sensitivity and specificity for the recognition of self and pathogens.The actin-driven spatiotemporal organization of T-cell signaling at the system scale.About supramolecular systems for dynamically probing cells.Organizing MHC Class II Presentation.
P2860
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P2860
T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
T-cell triggering thresholds a ...... dual T-cell receptor clusters.
@ast
T-cell triggering thresholds a ...... dual T-cell receptor clusters.
@en
type
label
T-cell triggering thresholds a ...... dual T-cell receptor clusters.
@ast
T-cell triggering thresholds a ...... dual T-cell receptor clusters.
@en
prefLabel
T-cell triggering thresholds a ...... dual T-cell receptor clusters.
@ast
T-cell triggering thresholds a ...... dual T-cell receptor clusters.
@en
P2093
P2860
P356
P1476
T-cell triggering thresholds a ...... dual T-cell receptor clusters.
@en
P2093
Boryana N Manz
Bryan L Jackson
Jay Groves
Rebecca S Petit
P2860
P304
P356
10.1073/PNAS.1018771108
P407
P577
2011-05-16T00:00:00Z