Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.
about
Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation.Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E.PLK1 phosphorylates mitotic centromere-associated kinesin and promotes its depolymerase activityCENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosisDynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachmentXAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE.SUV39H1 orchestrates temporal dynamics of centromeric methylation essential for faithful chromosome segregation in mitosis.Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules.Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregationIRE1-RACK1 axis orchestrates ER stress preconditioning-elicited cytoprotection from ischemia/reperfusion injury in liverPhosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore.Mechanisms of Chromosome Congression during Mitosis.Oncogenic role of kinesin proteins and targeting kinesin therapy.Mitosis as an anti-cancer drug target.Cenp-E inhibitor GSK923295: Novel synthetic route and use as a tool to generate aneuploidy.Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation.
P2860
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P2860
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.
@ast
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.
@en
type
label
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.
@ast
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.
@en
prefLabel
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.
@ast
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.
@en
P2093
P2860
P356
P1433
P1476
Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin
@en
P2093
Jiancun Zhang
Tongge Zhu
Weihong Wan
Xinjiao Gao
Xiwei Wang
Xuebiao Yao
P2860
P2888
P304
P356
10.1038/CR.2010.167
P577
2010-11-30T00:00:00Z