CENP-E function at kinetochores is essential for chromosome alignment. - Wikidata - wikimedia - TriplyDB

CENP-E function at kinetochores is essential for chromosome alignment.

CENP-E function at kinetochores is essential for chromosome alignment.

http://www.wikidata.org/entity/Q36254954

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Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1 Structural requirements and dynamics of mitosin-kinetochore interaction in M phase Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment.Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting CAS, the human homologue of the yeast chromosome-segregation gene CSE1, in proliferation, apoptosis, and cancer.The human chromokinesin Kid is a plus end-directed microtubule-based motor Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay A new look at kinetochore structure in vertebrate somatic cells using high-pressure freezing and freeze substitution SUMO-2/3 modification and binding regulate the association of CENP-E with kinetochores and progression through mitosis Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation Mitotic centromere-associated kinesin is important for anaphase chromosome segregation Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles The Ran Pathway in Drosophila melanogaster Mitosis Force generation by kinesin and myosin cytoskeletal motor proteins KNL1: bringing order to the kinetochore Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle SUMOylation in control of accurate chromosome segregation during mitosis Centromere protein F includes two sites that couple efficiently to depolymerizing microtubules Chromosomes can congress to the metaphase plate before biorientation.Bub1-mediated adaptation of the spindle checkpoint Suppressor analysis of a histone defect identifies a new function for the hda1 complex in chromosome segregation.TRAMM/TrappC12 plays a role in chromosome congression, kinetochore stability, and CENP-E recruitment.Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAK Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules A dominant mutant of inner centromere protein (INCENP), a chromosomal protein, disrupts prometaphase congression and cytokinesis Lateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila Oocytes Characterization of a novel kinetochore protein, CENP-H Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes.

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P2860

CENP-E function at kinetochores is essential for chromosome alignment.

http://www.wikidata.org/entity/Q36254954

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1997 nî lūn-bûn

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1997年論文

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1997年論文

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1997年论文

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1997年论文

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name

CENP-E function at kinetochores is essential for chromosome alignment.

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CENP-E function at kinetochores is essential for chromosome alignment.

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CENP-E function at kinetochores is essential for chromosome alignment.

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CENP-E function at kinetochores is essential for chromosome alignment.

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CENP-E function at kinetochores is essential for chromosome alignment.

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CENP-E function at kinetochores is essential for chromosome alignment.

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CENP-E function at kinetochores is essential for chromosome alignment

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B T Schaar

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E D Salmon

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P Maddox

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P2860

CENP-E is a putative kinetochore motor that accumulates just before mitosis

CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase

Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis

Mitotic HeLa cells contain a CENP-E-associated minus end-directed microtubule motor

Cytoplasmic dynein plays a role in mammalian mitotic spindle formation

Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindle

Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism

Kinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: direct visualization in live newt lung cells

Kinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onset

High-efficiency transformation of mammalian cells by plasmid DNA

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