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Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression

Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression

http://www.wikidata.org/entity/Q35023309

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Novel monoamine oxidase A knock out mice with human-like spontaneous mutation Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonist Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions A Review of Biomarkers in Mood and Psychotic Disorders: A Dissection of Clinical vs. Preclinical Correlates Astrocytic adenosine: from synapses to psychiatric disorders Biomarkers of epileptogenesis: psychiatric comorbidities (?)The lonely mouse - single housing affects serotonergic signaling integrity measured by 8-OH-DPAT-induced hypothermia in male mice The Role of Muscarinic Receptors in the Pathophysiology of Mood Disorders: A Potential Novel Treatment?Characterization of an mGluR2/3 negative allosteric modulator in rodent models of depression Chronic fluoxetine upregulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortex Common Mechanisms Underlying Epileptogenesis and the Comorbidities of Epilepsy.A genetic approach to access serotonin neurons for in vivo and in vitro studies.TASK-3 as a potential antidepressant target.Interleukin-15 affects serotonin system and exerts antidepressive effects through IL15Rα receptor.Quantitative traits for the tail suspension test: automation, optimization, and BXD RI mapping.Knockout of the norepinephrine transporter and pharmacologically diverse antidepressants prevent behavioral and brain neurotrophin alterations in two chronic stress models of depression.Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress.Antidepressant effects of sleep deprivation require astrocyte-dependent adenosine mediated signaling Enhanced Cocaine-Associated Contextual Learning in Female H/Rouen Mice Selectively Bred for Depressive-Like Behaviors: Molecular and Neuronal Correlates.Differential stress-induced neuronal activation patterns in mouse lines selectively bred for high, normal or low anxiety.Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level Sleep disturbances in highly stress reactive mice: modeling endophenotypes of major depression.Rhythmicity in mice selected for extremes in stress reactivity: behavioural, endocrine and sleep changes resembling endophenotypes of major depression Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling.Phenotypic characterization of a genetically diverse panel of mice for behavioral despair and anxiety.Vmat2 heterozygous mutant mice display a depressive-like phenotype.Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor function Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression.Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior.Rapid eye movements during sleep in mice: high trait-like stability qualifies rapid eye movement density for characterization of phenotypic variation in sleep patterns of rodents F15599, a highly selective post-synaptic 5-HT(1A) receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity.Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders.In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice.Sleep phenotyping in a mouse model of extreme trait anxiety.GABAB(1) receptor subunit isoforms differentially regulate stress resilience Mice do not habituate to metabolism cage housing--a three week study of male BALB/c mice.GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine Modeling treatment-resistant depression.Annual Research Review: New frontiers in developmental neuropharmacology: can long-term therapeutic effects of drugs be optimized through carefully timed early intervention?

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Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression

http://www.wikidata.org/entity/Q35023309

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2003年の論文

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PNAS.1034823100

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Proceedings of the National Academy of Sciences of the United States of America

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Behavioral, neurochemical, and ...... etic mouse model of depression

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P2093

Jean Costentin

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Jean-Marie Vaugeois

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Joëlle Adrien

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Laurent Naudon

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Malika El Yacoubi

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Michel Hamon

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Saoussen Bouali

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P2860

The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A(2A) receptors

Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity

Depression: a new animal model sensitive to antidepressant treatments

Role of the serotonergic system in the pathogenesis of major depression and suicidal behavior.

Autoregulation of serotonin neurons: role in antidepressant drug action.

Key role of 5-HT1B receptors in the regulation of paradoxical sleep as evidenced in 5-HT1B knock-out mice.

History and evolution of the monoamine hypothesis of depression.

Validity, reliability and utility of the chronic mild stress model of depression: a 10-year review and evaluation.

Assessing antidepressant activity in rodents: recent developments and future needs.

Behavioral characteristics of rat lines selected for differential hypothermic responses to cholinergic or serotonergic agonists.

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10

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100

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Isabelle Leroux-Nicollet

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10772224

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12732720

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electrophysiology

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156354

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