Cycling at the interface between neurodevelopment and neurodegeneration. - Wikidata - wikimedia - TriplyDB

Cycling at the interface between neurodevelopment and neurodegeneration.

Cycling at the interface between neurodevelopment and neurodegeneration.

http://www.wikidata.org/entity/Q35023927

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Inactivation of CDK/pRb pathway normalizes survival pattern of lymphoblasts expressing the FTLD-progranulin mutation c.709-1G>A SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis Role of p19ink4d in the pathogenesis of hearing loss.Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.Phosphoproteome and transcriptome analysis of the neuronal response to a CDK5 inhibitor.Neuronal injury external to the retina rapidly activates retinal glia, followed by elevation of markers for cell cycle re-entry and death in retinal ganglion cells Visualization and quantitation of the expression of microRNAs and their target genes in neuroblastoma single cells using imaging cytometry.A 24-residue peptide (p5), derived from p35, the Cdk5 neuronal activator, specifically inhibits Cdk5-p25 hyperactivity and tau hyperphosphorylation.Genetic determinants at the interface of cancer and neurodegenerative disease.Increased synaptophysin is involved in inflammation-induced heat hyperalgesia mediated by cyclin-dependent kinase 5 in rats.Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration.Neurodegeneration and neuroinflammation in cdk5/p25-inducible mice: a model for hippocampal sclerosis and neocortical degeneration.Cell cycle activation and spinal cord injury.The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease Bilateral gene interaction hierarchy analysis of the cell death gene response emphasizes the significance of cell cycle genes following unilateral traumatic brain injury Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress Dual action of the inhibitors of cyclin-dependent kinases: targeting of the cell-cycle progression and activation of wild-type p53 protein.TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration.Recent advances in neuroprotection for treating traumatic brain injury.Neurons in Vulnerable Regions of the Alzheimer's Disease Brain Display Reduced ATM Signaling.Membrane microdomain switching: a regulatory mechanism of amyloid precursor protein processing.MicroRNAs (miRNAs) in neurodegenerative diseases.Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma.Cdk5 and the non-catalytic arrest of the neuronal cell cycle.Bridging the Divide between Neuroprosthetic Design, Tissue Engineering and Neurobiology.Cell cycle deregulation in the neurons of Alzheimer's disease.miR-146a and miR-370 coordinate enterovirus 71-induced cell apoptosis through targeting SOS1 and GADD45β.Progranulin Deficiency Reduces CDK4/6/pRb Activation and Survival of Human Neuroblastoma SH-SY5Y Cells.Motor phenotypes and molecular networks associated with germline deficiency of Ciz1.HIV-1 Tat inhibits NGF-induced Egr-1 transcriptional activity and consequent p35 expression in neural cells.Chemotactic and mitogenic stimuli of neuronal apoptosis in patients with medically intractable temporal lobe epilepsy.Enterovirus 71 triggering of neuronal apoptosis through activation of Abl-Cdk5 signalling.The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling.The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons.Expression of gp100 and CDK2 in melanoma cells is not co-regulated by a shared promoter region.Targeting Cdk5 activity in neuronal degeneration and regeneration.ERK MAP kinase activation in spinal cord regulates phosphorylation of Cdk5 at serine 159 and contributes to peripheral inflammation induced pain/hypersensitivity Up-regulation of ski-interacting protein in rat brain cortex after traumatic brain injury.Cell injury and premature neurodegeneration in focal malformations of cortical development.MiRNA-124 is a link between measles virus persistent infection and cell division of human neuroblastoma cells.

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P2860

Cycling at the interface between neurodevelopment and neurodegeneration.

http://www.wikidata.org/entity/Q35023927

description

2002 nî lūn-bûn

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2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

@zh-hk

2002年論文

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2002年論文

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2002年论文

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name

Cycling at the interface between neurodevelopment and neurodegeneration.

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Cycling at the interface between neurodevelopment and neurodegeneration.

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Cycling at the interface between neurodevelopment and neurodegeneration.

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Cycling at the interface between neurodevelopment and neurodegeneration.

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prefLabel

Cycling at the interface between neurodevelopment and neurodegeneration.

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Cycling at the interface between neurodevelopment and neurodegeneration.

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Cell Death & Differentiation

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Cycling at the interface between neurodevelopment and neurodegeneration.

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P2093

Julien JP

http://www.w3.org/2001/XMLSchema#string

Mushynski WE

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Nguyen MD

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P2860

Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor

Expression of CDK5 (PSSALRE kinase), a neural cdc2-related protein kinase, in the mature and developing mouse central and peripheral nervous systems

An isoform of the neuronal cyclin-dependent kinase 5 (Cdk5) activator

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain

Structure and regulation of the CDK5-p25(nck5a) complex

A novel cdc2-related protein kinase expressed in the nervous system

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

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1294-1306

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10.1038/SJ.CDD.4401108

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12

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9

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10994852

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12478466

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