Viral-host interactions that control HIV-1 transcriptional elongation
about
P-TEFb goes viralHIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchTranscriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cureThe Old and New Testaments of gene regulation. Evolution of multi-subunit RNA polymerases and co-evolution of eukaryote complexity with the RNAP II CTDAFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoterBrd4 activates P-TEFb for RNA polymerase II CTD phosphorylationCracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFbA Natural Product from Polygonum cuspidatum Sieb. Et Zucc. Promotes Tat-Dependent HIV Latency Reversal through Triggering P-TEFb's Release from 7SK snRNPCharacterizing RNA ensembles from NMR data with kinematic models.LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis.Phenyl-1-Pyridin-2yl-ethanone-based iron chelators increase IκB-α expression, modulate CDK2 and CDK9 activities, and inhibit HIV-1 transcriptionCompensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanismGene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription.Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.Regulation of CDK9 activity by phosphorylation and dephosphorylation.Role of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription.Transcriptional Elongation of HSV Immediate Early Genes by the Super Elongation Complex Drives Lytic Infection and Reactivation from Latency.Recent advances in the identification of Tat-mediated transactivation inhibitors: progressing toward a functional cure of HIV.Improving combination antiretroviral therapy by targeting HIV-1 gene transcription.P-TEFb goes viral.Cell-penetrating, dimeric α-helical peptides: nanomolar inhibitors of HIV-1 transcription.The KAT5-Acetyl-Histone4-Brd4 axis silences HIV-1 transcription and promotes viral latency.Hacking the Cell: Network Intrusion and Exploitation by Adenovirus E1A.SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
P2860
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P2860
Viral-host interactions that control HIV-1 transcriptional elongation
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Viral-host interactions that control HIV-1 transcriptional elongation
@ast
Viral-host interactions that control HIV-1 transcriptional elongation
@en
type
label
Viral-host interactions that control HIV-1 transcriptional elongation
@ast
Viral-host interactions that control HIV-1 transcriptional elongation
@en
prefLabel
Viral-host interactions that control HIV-1 transcriptional elongation
@ast
Viral-host interactions that control HIV-1 transcriptional elongation
@en
P2093
P2860
P356
P1433
P1476
Viral-host interactions that control HIV-1 transcriptional elongation
@en
P2093
Huasong Lu
Qiang Zhou
Zichong Li
P2860
P304
P356
10.1021/CR400120Z
P577
2013-06-24T00:00:00Z