Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration. - Wikidata - wikimedia - TriplyDB

Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration.

Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration.

http://www.wikidata.org/entity/Q35027621

about

DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components Microfluidic co-cultures of retinal pigment epithelial cells and vascular endothelial cells to investigate choroidal angiogenesis.Mitochondrial disorders and the eye.Aging leads to elevation of O-GlcNAcylation and disruption of mitochondrial homeostasis in retina.Mitochondrial expression and activity of P-glycoprotein under oxidative stress in outer blood-retinal barrier Retinal mitochondrial DNA mismatch repair in the development of diabetic retinopathy, and its continued progression after termination of hyperglycemia.Effects of major ozonated autohemotherapy in the treatment of dry age related macular degeneration: a randomized controlled clinical study.Inflammatory cytokines protect retinal pigment epithelial cells from oxidative stress-induced death.Association of age-related macular degeneration with erythrocyte antioxidant enzymes activity and serum total antioxidant status.Investigating mitochondria as a target for treating age-related macular degeneration Genetic insights into age-related macular degeneration: controversies addressing risk, causality, and therapeutics.miR-17-3p Exacerbates Oxidative Damage in Human Retinal Pigment Epithelial Cells.Decreased Integrity, Content, and Increased Transcript Level of Mitochondrial DNA Are Associated with Keratoconus.Mechanisms for countering oxidative stress and damage in retinal pigment epithelium.PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity.Simultaneous determination of 8-oxo-2'-deoxyguanosine and 8-oxo-2'-deoxyadenosine in human retinal DNA by liquid chromatography nanoelectrospray-tandem mass spectrometry Oxidative stress, innate immunity, and age-related macular degeneration Mitochondrial elongation in the macular RPE of aging monkeys, evidence of metabolic stress.Amyloid β peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system Artemisinin protects human retinal pigment epithelial cells from hydrogen peroxide-induced oxidative damage through activation of ERK/CREB signaling.Klotho regulates retinal pigment epithelial functions and protects against oxidative stress.Aging is not a disease: distinguishing age-related macular degeneration from aging.Antioxidant drug therapy approaches for neuroprotection in chronic diseases of the retina.Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration.Consequences of oxidative stress in age-related macular degeneration.Oxidative Stress and the Nrf2 Anti-Oxidant Transcription Factor in Age-Related Macular Degeneration.Targeting mitochondrial function to protect against vision loss.Cell-based therapeutic strategies for replacement and preservation in retinal degenerative diseases.Drusen maculopathy: a risk factor for visual deterioration.Mitochondrial DNA has a pro-inflammatory role in AMD.The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD.The role and therapeutic potential of melatonin in age-related ocular diseases.Chaperone-independent mitochondrial translocation and protection by αB-crystallin in RPE cells.Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR.Mitochondrial and nuclear DNA damage and repair in age-related macular degeneration.mTOR pathway activation in age-related retinal disease.Essential role of β-human 8-oxoguanine DNA glycosylase 1 in mitochondrial oxidative DNA repair.

P2860

Q24621930-CDFF1A41-54A3-4873-977F-DAE92800A4D3 Q27008407-E3F3BB05-E3A9-452D-A1FB-A61A918B2702 Q28482106-53B8907E-9167-453C-BBFA-5ECC0E572E67 Q30576000-1996666B-8FE9-4943-97A1-C3C9178988AB Q30855748-C0204BD6-FFCD-453F-B573-F6E1872B6FD2 Q33702120-46BF1931-455B-4848-984A-883D0B62AED0 Q33765402-980C1DAD-4DD3-404B-BDEB-12139656C968 Q33912457-912ADB2B-C201-412A-9B63-7FAA6F0C6B9B Q34433611-394470B1-C223-4B00-9C07-841D2D373E42 Q34646906-CD066DB7-120F-44C5-80E3-7B7F0ADD481B Q34738110-DAD25B94-0040-481F-8B7D-8A167B76AAA0 Q35177952-855A6374-52EC-4C6E-9322-4ECDCCAA5064 Q35572570-6EF79FDB-2611-445C-A33E-36E720BEA341 Q36084168-59A0DF18-EF78-406F-AE1D-534347B6011E Q36098826-9972CFA3-9A2A-4C86-8FF4-0B2D5B4A5E31 Q36175121-EED607F3-C893-4FC8-9D3D-3C93206B514C Q36587125-17B5F25D-47C4-4492-A132-DDD465E54B15 Q36676999-16B1B706-BAA7-4875-A216-95C5DA99860F Q36690876-A66D4425-064A-48DF-A3F6-F2EB4D642B1E Q36940296-F6DBF5EC-76CB-4604-B17A-A55B4D757C2E Q36945891-0F8453A5-84B8-4680-A8A5-7EA66CDF49A6 Q36961203-BAB6E0D6-207A-4BFA-BB6E-C435B0ABDBC4 Q37081129-F43A564C-D997-4AB3-898F-9CC7B0E63E8C Q37261449-DD199B1B-C23D-45C7-B295-D5A59A714C0C Q37315838-7B9E44C5-1400-482E-81C5-8264499BF4B3 Q37645117-381AA7F4-65E7-43A5-A627-DF65494C473E Q37744895-E97B856D-327C-4EFD-8637-30D514AE7BF7 Q38003229-E3A98E78-9F7C-44CA-805F-A9928A7352A9 Q38596849-B267542D-EBFD-4933-AACA-91958349978A Q38694794-E82793CB-CA04-44B1-8DE9-C035FA529DD5 Q38767261-0B1B8ED7-FCD3-4EBE-B9A0-9E1C2D95FD42 Q38786743-68FB1AEF-6350-40AF-8626-5B8A6094A44C Q38841002-430A511F-1E2B-4A37-B563-8163CAB495A5 Q39197341-6556C94A-9AA4-4388-BF88-CCA2A2A4B81F Q39402838-B3472FD0-FF57-4B40-BCD1-747239A3D23B Q40062235-BFC8435E-A116-46F3-8731-676049D2B89A Q40360920-BE7EF48B-6778-4BC2-B480-9DA4B7A9176C Q41617454-A2BA6DA4-3DB2-4CF5-9193-452C02A26DA2 Q42762402-EC801C70-1678-4BF8-A956-B20907021B3F Q44617054-F4E087C4-A930-4C13-AD37-7D75447F6BD2

P2860

Mitochondrial DNA damage and repair in RPE associated with aging and age-related macular degeneration.

http://www.wikidata.org/entity/Q35027621

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Mitochondrial DNA damage and r ...... -related macular degeneration.

@ast

Mitochondrial DNA damage and r ...... -related macular degeneration.

@en

type

label

Mitochondrial DNA damage and r ...... -related macular degeneration.

@ast

Mitochondrial DNA damage and r ...... -related macular degeneration.

@en

prefLabel

Mitochondrial DNA damage and r ...... -related macular degeneration.

@ast

Mitochondrial DNA damage and r ...... -related macular degeneration.

@en

P1433

Q35027621-D192F04F-F3AA-48B9-9178-70296F5EAEB4

P1476

Q35027621-C1A386FC-8550-41FB-AB84-619673D50477

P2093

Q35027621-364E9C45-6D5F-4392-AEB9-2120BD3C4A48

Q35027621-49A535C5-8116-41DE-AF03-8E0922ACC842

Q35027621-5F133E6B-4F6C-4563-BB30-21A4FB8A3614

Q35027621-709EFF3E-F993-41C5-B7B5-A01331E47A1D

Q35027621-8723E53E-3228-47D7-A7BD-36AFFCC320EB

Q35027621-AA6B572D-D730-4400-9398-91F9A5D478C4

Q35027621-BC9ADF5A-F0D2-43E7-864F-03B406C50FDA

Q35027621-BFE7C283-98B1-4FC4-9B77-56D33194E605

P2860

Q35027621-01E47B00-8E25-499E-8710-3EF4AB19C9FD

Q35027621-02AA4AE7-CC17-4E19-916F-D3E36E1575D6

Q35027621-0DE71EC6-9F51-4E51-9D9B-B8D711C59EF3

Q35027621-16112958-1B91-4886-AF3C-5F8FAA5FD304

Q35027621-181A0E12-D505-4C5A-8E48-FA7F215C3C56

Q35027621-29A0BA4D-7E08-422D-A10D-DE4D982FAD8E

Q35027621-2D58028B-FD5A-4767-8C30-6A6287BD62EB

Q35027621-3079CDCF-F354-4F3A-B283-6A99AECB11A9

Q35027621-3909AC14-8D80-4E35-A3BF-A91CC68037AA

Q35027621-3E2B3002-A2F9-4AB4-883D-CBD8A31BDF38

P304

Q35027621-C7C37CE0-6C34-4A9A-ACA3-5333B69980B3

P31

Q35027621-BA3F2CB6-48E6-46DF-9CA3-0988D5CE0118

P356

Q35027621-19FFE811-84A5-429C-9D2F-CCD3A557402B

P407

Q35027621-09784070-420E-4B1C-91A1-87D9D05C33E7

P433

Q35027621-4694AA3E-2EEF-46CD-A208-3D674425FB9A

P478

Q35027621-58FC2E14-ACCC-4222-B7F4-2224F99CF638

P577

Q35027621-A2A74486-8F9E-4A5B-B62B-0F21BB11E6D1

P5875

Q35027621-550C87A2-74D9-4749-8B36-EBBC3C3C6477

P698

Q35027621-C5F254E8-A3DB-4CFE-A145-682949FC1BEC

P921

Q35027621-0AD7D0A9-54F7-4F6E-9054-6ACE66A83612

Q35027621-61B35D00-482C-4811-A78E-9F7A29EC834D

P932

Q35027621-C58345D1-5E8D-47C4-A01C-A5DCE2F06DFF

P356

P1433

Investigative Ophthalmology & Visual Science

P1476

Mitochondrial DNA damage and r ...... -related macular degeneration.

@en

P2093

Anna N Havey

http://www.w3.org/2001/XMLSchema#string

Bernard F Godley

http://www.w3.org/2001/XMLSchema#string

Fong-Qi Liang

http://www.w3.org/2001/XMLSchema#string

Haifeng Xu

http://www.w3.org/2001/XMLSchema#string

Haijiang Lin

http://www.w3.org/2001/XMLSchema#string

Hao Liang

http://www.w3.org/2001/XMLSchema#string

Michael E Boulton

http://www.w3.org/2001/XMLSchema#string

Praveena Gupta

http://www.w3.org/2001/XMLSchema#string

P2860

Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.

Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1

Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice

Oxidative stress-induced retinal damage up-regulates DNA polymerase gamma and 8-oxoguanine-DNA-glycosylase in photoreceptor synaptic mitochondria

Mitochondrial function and redox control in the aging eye: role of MsrA and other repair systems in cataract and macular degenerations

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

The Minnesota Grading System of eye bank eyes for age-related macular degeneration.

Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration.

Age-related macular degeneration--emerging pathogenetic and therapeutic concepts.

Base excision repair in nuclear and mitochondrial DNA.

P304

3521-3529

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1167/IOVS.10-6163

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

52

http://www.w3.org/2001/XMLSchema#string

P577

2011-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

49791296

http://www.w3.org/2001/XMLSchema#string

P698

21273542

http://www.w3.org/2001/XMLSchema#string

P921

mitochondrial DNA

P932

3109040

http://www.w3.org/2001/XMLSchema#string