Functional and molecular biological evidence for a possible beta3-adrenoceptor in the human detrusor muscle
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The role of beta(3)-adrenoceptors in mediating relaxation of porcine detrusor muscleCan the adrenergic system be implicated in the pathophysiology of bladder pain syndrome/interstitial cystitis? A clinical and experimental studyComparative 3D QSAR study on β(1)-, β(2)-, and β(3)-adrenoceptor agonistsDiscovery history and clinical development of mirabegron for the treatment of overactive bladder and urinary incontinence.Pharmacologic characteristics of bladder micturition function in anesthetized miceBeta3-adrenoceptor agonists: possible role in the treatment of overactive bladderMixed symptomatology.β-Adrenergic receptor subtype expression in myocyte and non-myocyte cells in human female bladder.Prospective pharmacologic therapies for the overactive bladderOveractive bladder in malesAlpha1-, alpha2- and beta-adrenoceptors in the urinary bladder, urethra and prostate.Mirabegron relaxes urethral smooth muscle by a dual mechanism involving β3 -adrenoceptor activation and α1 -adrenoceptor blockadeCurrent and emerging investigational medical therapies for the treatment of overactive bladder.Stimulation of beta3-adrenoceptors relaxes rat urinary bladder smooth muscle via activation of the large-conductance Ca2+-activated K+ channels.A phase II dose-ranging study of mirabegron in patients with overactive bladderMirabegron for the treatment of overactive bladder: a prespecified pooled efficacy analysis and pooled safety analysis of three randomised, double-blind, placebo-controlled, phase III studies.A functional analysis of the influence of β3-adrenoceptors on the rat micturition cycleLatest treatment for lower urinary tract dysfunction: therapeutic agents and mechanism of action.What do we know and not know about mirabegron, a novel β3 agonist, in the treatment of overactive bladder?Solabegron: a potential future addition to the β-3 adrenoceptor agonist armamentarium for the management of overactive bladder.Early investigational β3 adreno-receptor agonists for the management of the overactive bladder syndrome.Current and future pharmacotherapy for treating overactive bladder.Expression of β-Adrenoceptor Subtypes in Urothelium, Interstitial Cells and Detrusor of the Human Urinary Bladder.Urine retention in a child treated with oral salbutamolEffects of beta(3)-adrenoceptor stimulation on prostaglandin E(2)-induced bladder hyperactivity and on the cardiovascular system in conscious rats.A proof-of-concept study: mirabegron, a new therapy for overactive bladder.Association between polymorphism of beta3-adrenoceptor gene and overactive bladder.Functional investigation of β-adrenoceptors in human isolated detrusor focusing on the novel selective β3-adrenoceptor agonist KUC-7322.Effects of a novel beta(3)-adrenoceptor agonist, AJ-9677, on relaxation of the detrusor muscle: an in vitro study.Relaxant effects of beta-adrenergic agonists on porcine and human detrusor muscle.In vitro alpha-adrenoceptor autoradiography of the urethra and urinary bladder of the female pig, cat, guinea-pig and rat.Phase III Study to Assess Long-Term (52-Week) Safety and Efficacy of Mirabegron, a β3 -Adrenoceptor Agonist, in Japanese Patients with Overactive Bladder.Mucosa of human detrusor impairs contraction and β-adrenoceptor-mediated relaxation.2D-QSAR and 3D-QSAR/CoMSIA Studies on a Series of (R)-2-((2-(1H-Indol-2-yl)ethyl)amino)-1-Phenylethan-1-ol with Human β₃-Adrenergic Activity.Comparison of mirabegron and imidafenacin for efficacy and safety in Japanese female patients with overactive bladder: A randomized controlled trial (COMFORT study).Non-adrenergic, non-cholinergic, non-purinergic contractions of the urothelium/lamina propria of the pig bladder.Excitatory effect of propiverine hydrochloride on urethral activity in rats.β3-Adrenoceptor agonist mirabegron is effective for overactive bladder that is unresponsive to antimuscarinic treatment or is related to benign prostatic hyperplasia in men.Urodynamic Efficacy and Safety of Mirabegron Add-on Treatment with Tamsulosin for Japanese Male Patients with Overactive Bladder.β3-adrenoceptor agonists inhibit carbachol-evoked Ca2+ oscillations in murine detrusor myocytes.
P2860
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P2860
Functional and molecular biological evidence for a possible beta3-adrenoceptor in the human detrusor muscle
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Functional and molecular biolo ...... r in the human detrusor muscle
@ast
Functional and molecular biolo ...... r in the human detrusor muscle
@en
type
label
Functional and molecular biolo ...... r in the human detrusor muscle
@ast
Functional and molecular biolo ...... r in the human detrusor muscle
@en
prefLabel
Functional and molecular biolo ...... r in the human detrusor muscle
@ast
Functional and molecular biolo ...... r in the human detrusor muscle
@en
P2093
P2860
P356
P1476
Functional and molecular biolo ...... r in the human detrusor muscle
@en
P2093
K E Andersson
K Hayakawa
O Nishizawa
T Yoneyama
Y Yamazaki
P2860
P304
P356
10.1038/SJ.BJP.0702358
P407
P577
1999-02-01T00:00:00Z