(-)-CGP 12177-induced increase of human atrial contraction through a putative third beta-adrenoceptor
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beta(1)-Adrenoceptors compensate for beta(3)-adrenoceptors in ileum from beta(3)-adrenoceptor knock-out miceEffects of (-)-RO363 at human atrial beta-adrenoceptor subtypes, the human cloned beta 3-adrenoceptor and rodent intestinal beta 3-adrenoceptorsHuman atrial β(1L)-adrenoceptor but not β₃-adrenoceptor activation increases force and Ca(2+) current at physiological temperature.Lipolytic effects of conventional beta 3-adrenoceptor agonists and of CGP 12,177 in rat and human fat cells: preliminary pharmacological evidence for a putative beta 4-adrenoceptorValidity of (-)-[3H]-CGP 12177A as a radioligand for the 'putative beta4-adrenoceptor' in rat atrium.Species differences in the distribution of beta-adrenoceptor subtypes in bladder smooth muscle.Functional and molecular biological evidence for a possible beta3-adrenoceptor in the human detrusor muscleBeta 3-adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium-derived nitric oxide in rat thoracic aortaDesensitization and resensitization of beta 1- and putative beta 4-adrenoceptor mediated responses occur in parallel in a rat model of cardiac failurePutative beta 4-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[3H]-CGP 12177 binding.Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wildtype and beta(3)-adrenoceptor knockout mice.Overexpression of beta 1-adrenoceptors in adult rat ventricular myocytes enhances CGP 12177A cardiostimulation: implications for 'putative' beta 4-adrenoceptor pharmacologyDownregulation of propranolol-sensitive beta-adrenoceptor signaling after inhibition of nitric oxide synthesisDifferences between the third cardiac beta-adrenoceptor and the colonic beta 3-adrenoceptor in the rat.Tools to study beta3-adrenoceptors.Human heart beta-adrenoceptors: beta1-adrenoceptor diversification through 'affinity states' and polymorphism.Chronic activation of the low affinity site of β1-adrenoceptors stimulates haemodynamics but exacerbates pressure-overload cardiac remodelling.The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.Phosphodiesterase PDE3 blunts the positive inotropic and cyclic AMP enhancing effects of CGP12177 but not of noradrenaline in rat ventricleA study of antagonist affinities for the human histamine H2 receptor.Proposal for the interaction of non-conventional partial agonists and catecholamines with the 'putative beta 4-adrenoceptor' in mammalian heart.Aryl propanolamines: comparison of activity at human beta3 receptors, rat beta3 receptors and rat atrial receptors mediating tachycardia.Further evidence for differences between cardiac atypical beta-adrenoceptors and brown adipose tissue beta3-adrenoceptors in the pithed rat.Positive inotropic and lusitropic effects mediated via the low-affinity state of beta1-adrenoceptors in pithed rats.Stimulation of cyclic AMP-dependent protein kinase in rat atria by (-)-CGP 12177 through an atypical beta-adrenoceptor.Markedly reduced effects of (-)-isoprenaline but not of (-)-CGP12177 and unchanged affinity of beta-blockers at Gly389-beta1-adrenoceptors compared to Arg389-beta1-adrenoceptors.Beta 1-, beta 2- and atypical beta-adrenoceptor-mediated relaxation in rat isolated aorta.Atypical cardiostimulant beta-adrenoceptor in the rat heart: stereoselective antagonism by bupranolol but lack of effect by some bupranolol analogues.Pharmacological characterization of CGP 12177 at the human beta(2)-adrenoceptor.Comparison of the affinity of beta-blockers for two states of the beta 1-adrenoceptor in ferret ventricular myocardium.Partial agonistic activity of labetalol, the arylethanolamine, on beta 3-adrenoceptors in the guinea-pig gastric fundus.Phosphodiesterases PDE3 and PDE4 jointly control the inotropic effects but not chronotropic effects of (-)-CGP12177 despite PDE4-evoked sinoatrial bradycardia in rat atrium.Relaxant effects of beta-adrenergic agonists on porcine and human detrusor muscle.The effects of both noradrenaline and CGP12177, mediated through human beta1 -adrenoceptors, are reduced by PDE3 in human atrium but PDE4 in CHO cells.Peripheral cardiovascular actions of SR 58611 A, a beta 3-adrenoceptor agonist, in the dog: lack of central effect
P2860
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P2860
(-)-CGP 12177-induced increase of human atrial contraction through a putative third beta-adrenoceptor
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
(-)-CGP 12177-induced increase ...... tative third beta-adrenoceptor
@ast
(-)-CGP 12177-induced increase ...... tative third beta-adrenoceptor
@en
type
label
(-)-CGP 12177-induced increase ...... tative third beta-adrenoceptor
@ast
(-)-CGP 12177-induced increase ...... tative third beta-adrenoceptor
@en
prefLabel
(-)-CGP 12177-induced increase ...... tative third beta-adrenoceptor
@ast
(-)-CGP 12177-induced increase ...... tative third beta-adrenoceptor
@en
P2860
P1476
(-)-CGP 12177-induced increase ...... tative third beta-adrenoceptor
@en
P2093
A J Kaumann
P2860
P356
10.1111/J.1476-5381.1996.TB15159.X
P407
P577
1996-01-01T00:00:00Z