Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts.

Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts.

Item
http://www.wikidata.org/entity/Q35034285
Aurora-A Kinase as a Promising Therapeutic Target in CancerHistone deacetylase inhibitor trichostatin A enhances the antitumor effect of the oncolytic adenovirus H101 on esophageal squamous cell carcinoma in vitro and in vivo.The mitotic kinase Aurora--a promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα(+) breast cancer cells.Inhibition of Cdk2 kinase activity selectively targets the CD44⁺/CD24⁻/Low stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells.Loss of breast epithelial marker hCLCA2 promotes epithelial-to-mesenchymal transition and indicates higher risk of metastasisMultiple breast cancer cell-lines derived from a single tumor differ in their molecular characteristics and tumorigenic potentialObesity, independent of p53 gene dosage, promotes mammary tumor progression and upregulates the p53 regulator microRNA-504.Three interrelated themes in current breast cancer research: gene addiction, phenotypic plasticity, and cancer stem cells.Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathwayInhibition of Cdk2 activity decreases Aurora-A kinase centrosomal localization and prevents centrosome amplification in breast cancer cells.
P2860

Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts.

Item
http://www.wikidata.org/entity/Q35034285
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Abrogation of p53 function lea ...... uman breast cancer xenografts.
@ast
Abrogation of p53 function lea ...... uman breast cancer xenografts.
@en
type
label
Abrogation of p53 function lea ...... uman breast cancer xenografts.
@ast
Abrogation of p53 function lea ...... uman breast cancer xenografts.
@en
prefLabel
Abrogation of p53 function lea ...... uman breast cancer xenografts.
@ast
Abrogation of p53 function lea ...... uman breast cancer xenografts.
@en
P1433
P1476
P2093
P2860
P304
P31
P433
P478
P50
P577
P698
P921
P932
P1433
P1476
Abrogation of p53 function lea ...... uman breast cancer xenografts.
@en
P2093
P2860
P304
P31
P433
P478
P50
P577
P698
P921
P932