Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells - Wikidata - wikimedia - TriplyDB

Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

http://www.wikidata.org/entity/Q35034700

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Cancer stem cells: a metastasizing menace!Concise Review: Stem Cells in Pancreatic Cancer: From Concept to Translation Chemotherapy targeting cancer stem cells Metformin as a new anti-cancer drug in adrenocortical carcinoma Metformin Treatment Does Not Inhibit Growth of Pancreatic Cancer Patient-Derived Xenografts Human Pancreatic Cancer-Associated Stellate Cells Remain Activated after in vivo Chemoradiation.Expression and Clinical Significance of Cancer Stem Cell Markers CD24, CD44, and CD133 in Pancreatic Ductal Adenocarcinoma and Chronic Pancreatitis Metformin against cancer stem cells through the modulation of energy metabolism: special considerations on ovarian cancer.Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation.Targeting the K-Ras--JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation.Metformin may function as anti-cancer agent via targeting cancer stem cells: the potential biological significance of tumor-associated miRNAs in breast and pancreatic cancers Challenges and future directions in therapeutics for pancreatic ductal adenocarcinoma.Diabetes, pancreatic cancer, and metformin therapy.Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells.Impact of diabetes type II and chronic inflammation on pancreatic cancer.Embryonic stem cell factors and pancreatic cancer New insights into pancreatic cancer stem cells.A concise review on the current understanding of pancreatic cancer stem cells Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors Phase II trial of metformin and paclitaxel for patients with gemcitabine-refractory advanced adenocarcinoma of the pancreas.Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies Metformin Increases Sensitivity of Pancreatic Cancer Cells to Gemcitabine by Reducing CD133+ Cell Populations and Suppressing ERK/P70S6K Signaling.5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits.Cancer stem cells and chemoresistance: The smartest survives the raid Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma.Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer.Dynamic Interactions Between Cancer Stem Cells And Their Stromal Partners.Metformin and cancer: Quo vadis et cui bono?Metformin enhances the radiosensitivity of human liver cancer cells to γ-rays and carbon ion beams.New molecules and old drugs as emerging approaches to selectively target human glioblastoma cancer stem cells.Metabostemness: a new cancer hallmark.The double-edged sword of AMPK signaling in cancer and its therapeutic implications.Existing drugs and their application in drug discovery targeting cancer stem cells.Targeting cancer cell metabolism in pancreatic adenocarcinoma.Metformin and prostate cancer stem cells: a novel therapeutic target.Metformin and pancreatic cancer: Is there a role?Effects of Metformin and a Mammalian Target of Rapamycin (mTOR) ATP-Competitive Inhibitor on Targeted Metabolomics in Pancreatic Cancer Cell Line.Mitochondria and Cancer.Metformin and Prostate Cancer: a New Role for an Old Drug.Metformin in pancreatic cancer treatment: from clinical trials through basic research to biomarker quantification.

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P2860

Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

http://www.wikidata.org/entity/Q35034700

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2013 nî lūn-bûn

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2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

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Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells

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Christopher Heeschen

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Enza Lonardo

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Jorge Dorado

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Yolanda Sanchez-Ripoll

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P2860

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Targeting the mTOR signaling network for cancer therapy

Cancer statistics, 2010

Epidemiology of pancreatic cancer

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

Metformin and reduced risk of cancer in diabetic patients

Pancreatic cancer

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Patricia Sancho

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258350833

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