MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity - Wikidata - wikimedia - TriplyDB

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity

http://www.wikidata.org/entity/Q35045715

about

A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid Development of Broad-Spectrum Halomethyl Ketone Inhibitors Against Coronavirus Main Protease 3CLpro Partial cleavage of RasGAP by caspases is required for cell survival in mild stress conditions.Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO.A sensitive near-infrared fluorescent probe for caspase-mediated apoptosis: Synthesis and application in cell imaging.Small Molecule Active Site Directed Tools for Studying Human Caspases Protective effect of 20-HETE inhibition in a model of oxygen-glucose deprivation in hippocampal slice cultures.Caspases: potential targets for regulating cell death.Genetic maneuvers to ameliorate ventricular function in heart failure: therapeutic potential and future implications.Molecular biology of apoptosis in ischemia and reperfusion.Remote preconditioning, perconditioning, and postconditioning: a comparative study of their cardio-protective properties in rat models In vivo administration of calpeptin attenuates calpain activation and cardiomyocyte loss in pressure-overloaded feline myocardium.Mechanisms of cell death in heart disease.Cell biology of ischemia/reperfusion injury.The TAT-RasGAP317-326 anti-cancer peptide can kill in a caspase-, apoptosis-, and necroptosis-independent manner.Strategies in the design of small-molecule fluorescent probes for peptidases.Functional properties of a novel hybrid antimicrobial peptide NS: potent antitumor activity and efficient plasmid delivery.TAT-RasGAP317-326-mediated tumor cell death sensitization can occur independently of Bax and Bak.Ischemia/Reperfusion.Effect of a caspase inhibitor, zVADfmk, on the inhibition of breast cancer cells by herpes simplex virus type 1.Tetramethylphenylenediamine protects the isolated heart against ischaemia-induced apoptosis and reperfusion-induced necrosis.Apoptosis in health and disease and modulation of apoptosis for therapy: An overview Mice overexpressing human caspase 3 appear phenotypically normal but exhibit increased apoptosis and larger lesion volumes in response to transient focal cerebral ischaemia.

P2860

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P2860

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity

http://www.wikidata.org/entity/Q35045715

description

2003 nî lūn-bûn

@nan

2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity

@en

type

label

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity

@en

prefLabel

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity

@en

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P1433

British Journal of Pharmacology

P1476

MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity

@en

P2093

Ben Tseng

http://www.w3.org/2001/XMLSchema#string

Dong Xue

http://www.w3.org/2001/XMLSchema#string

Jin-Cheng Huang

http://www.w3.org/2001/XMLSchema#string

John Drewe

http://www.w3.org/2001/XMLSchema#string

John Guastella

http://www.w3.org/2001/XMLSchema#string

Li Zhang

http://www.w3.org/2001/XMLSchema#string

Minhtam Tran

http://www.w3.org/2001/XMLSchema#string

Richard Woodward

http://www.w3.org/2001/XMLSchema#string

Shailaja Kasibhatla

http://www.w3.org/2001/XMLSchema#string

Sui Xiong Cai

http://www.w3.org/2001/XMLSchema#string

P2860

Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone

Apoptosis in the pathogenesis and treatment of disease

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Caspases: enemies within

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

The domains of death: evolution of the apoptosis machinery.

P304

402-412

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scholarly article

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10.1038/SJ.BJP.0705450

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P407

P433

2

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P478

140

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P577

2003-08-26T00:00:00Z

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10571324

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12970077

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1574042

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