Function and regulation of the mammalian copper-transporting ATPases: insights from biochemical and cell biological approaches.
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The distinct functional properties of the nucleotide-binding domain of ATP7B, the human copper-transporting ATPase: analysis of the Wilson disease mutations E1064A, H1069Q, R1151H, and C1104FA single PDZ domain protein interacts with the Menkes copper ATPase, ATP7A. A new protein implicated in copper homeostasisSolution structure of the N-domain of Wilson disease protein: distinct nucleotide-binding environment and effects of disease mutationsArabidopsis HMA2, a divalent heavy metal-transporting P(IB)-type ATPase, is involved in cytoplasmic Zn2+ homeostasisMolecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypesRegulation of brain iron and copper homeostasis by brain barrier systems: implication in neurodegenerative diseasesMechanistic insights into Cu(I) cluster transfer between the chaperone CopZ and its cognate Cu(I)-transporting P-type ATPase, CopAGGA2- and ubiquitin-dependent trafficking of Arn1, the ferrichrome transporter of Saccharomyces cerevisiaeA cadmium-transporting P1B-type ATPase in yeast Saccharomyces cerevisiae.A mutational study in the transmembrane domain of Ccc2p, the yeast Cu(I)-ATPase, shows different roles for each Cys-Pro-Cys cysteine.The copper toxicosis gene product Murr1 directly interacts with the Wilson disease proteinStructure, function, and regulation of a subfamily of mouse zinc transporter genesStructural biology of copper traffickingRole of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicityA novel role for the immunophilin FKBP52 in copper transportNH2-terminal signals in ATP7B Cu-ATPase mediate its Cu-dependent anterograde traffic in polarized hepatic cellsMetal binding to the N-terminal cytoplasmic domain of the PIB ATPase HMA4 is required for metal transport in Arabidopsis.Essential roles in development and pigmentation for the Drosophila copper transporter DmATP7.Control of metazoan heme homeostasis by a conserved multidrug resistance protein.Copper toxicosis gene MURR1 is not changed in Wilson disease patients with normal blood ceruloplasmin levels.A combined zinc/cadmium sensor and zinc/cadmium export regulator in a heavy metal pump.Ctr1 is an apical copper transporter in mammalian intestinal epithelial cells in vivo that is controlled at the level of protein stabilityMetal chaperones: a holistic approach to the treatment of Alzheimer's diseaseReview article: diagnosis and current therapy of Wilson's disease.Mechanisms of the copper-dependent turnover of the copper chaperone for superoxide dismutase.Structure of human Wilson protein domains 5 and 6 and their interplay with domain 4 and the copper chaperone HAH1 in copper uptake.Expression of a vacuole-localized BURP-domain protein from soybean (SALI3-2) enhances tolerance to cadmium and copper stresses.Canine models of copper toxicosis for understanding mammalian copper metabolism.Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity.In vivo correction of a Menkes disease model using antisense oligonucleotides.Expressional control of a cadmium-transporting P1B-type ATPase by a metal sensing degradation signal.ATP7A is a novel target of retinoic acid receptor beta2 in neuroblastoma cells.Apical targeting and Golgi retention signals reside within a 9-amino acid sequence in the copper-ATPase, ATP7B.Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptomsCopper-dependent recycling of hCTR1, the human high affinity copper transporter.Mammalian metallothionein in toxicology, cancer, and cancer chemotherapy.Copper-induced hepatitis: the COMMD1 deficient dog as a translational animal model for human chronic hepatitis.Absolute quantitation of protein therapeutics in biological matrices by enzymatic digestion and LC-MS.Interaction of metal ions with neurotransmitter receptors and potential role in neurodiseases.Bacterial Cu(+)-ATPases: models for molecular structure-function studies.
P2860
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P2860
Function and regulation of the mammalian copper-transporting ATPases: insights from biochemical and cell biological approaches.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Function and regulation of the ...... nd cell biological approaches.
@en
type
label
Function and regulation of the ...... nd cell biological approaches.
@en
prefLabel
Function and regulation of the ...... nd cell biological approaches.
@en
P1476
Function and regulation of the ...... nd cell biological approaches.
@en
P2093
P2888
P356
10.1007/S00232-002-1040-6
P577
2003-01-01T00:00:00Z