Endothelial destabilization by angiopoietin-2 via integrin β1 activation.
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Angiopoietins and diabetic nephropathyβ1 Integrins as Therapeutic Targets to Disrupt Hallmarks of CancerBiomarkers for Sepsis: What Is and What Might Be?Angiopoietin-Tie signalling in the cardiovascular and lymphatic systemsPlectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks.Tie1 controls angiopoietin function in vascular remodeling and inflammation.Intravenous neutralization of vascular endothelial growth factor reduces vascular function/permeability of the ovary and prevents development of OHSS-like symptoms in rhesus monkeysEfficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1Phosphorylation of Threonine 794 on Tie1 by Rac1/PAK1 Reveals a Novel Angiogenesis Regulatory Pathway.MARCKS Signaling Differentially Regulates Vascular Smooth Muscle and Endothelial Cell Proliferation through a KIS-, p27kip1- Dependent Mechanism.Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice.Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin.Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin.Gene control of tyrosine kinase TIE2 and vascular manifestations of infections.Effects of Percutaneous Coronary Intervention on Serum Angiopoietin-2 in Patients with Coronary Heart DiseaseElevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Nonsurgical Bleeding.Suppression of KSHV-induced angiopoietin-2 inhibits angiogenesis, infiltration of inflammatory cells, and tumor growth.MiR-145 functions as a tumor suppressor via regulating angiopoietin-2 in pancreatic cancer cells.Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activationAngiopoietin-2 promotes ER+ breast cancer cell survival in bone marrow niche.Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1.Heterogeneous perivascular cell coverage affects breast cancer metastasis and response to chemotherapySystems biological understanding of the regulatory network and the possible therapeutic strategies for vascular calcification.Cervical cancer cell-derived angiopoietins promote tumor progression.MCU-dependent mitochondrial Ca(2+) inhibits NAD(+)/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells.Angiogenic and Restorative Abilities of Human Mesenchymal Stem Cells Were Reduced Following Treatment With Serum From Diabetes Mellitus Type 2 Patients.Endothelial glycocalyx breakdown is mediated by angiopoietin-2.Therapeutic targeting of the angiopoietin-TIE pathway.Angiopoietins and Tie2 in vascular inflammation.Angiopoietin-1 deficiency increases tumor metastasis in mice.DT-13 Ameliorates TNF-α-Induced Vascular Endothelial Hyperpermeability via Non-Muscle Myosin IIA and the Src/PI3K/Akt Signaling PathwayCell-matrix signals specify bone endothelial cells during developmental osteogenesis.Angiopoietin-2: marker or mediator of angiogenesis in continuous-flow left ventricular assist device patients?Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts.Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels.Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP.Prevascularization of natural nanofibrous extracellular matrix for engineering completely biological three-dimensional prevascularized tissues for diverse applications.Angiopoietin-1 is required for Schlemm's canal development in mice and humans.Contribution of Adipose Tissue to Development of Cancer.CD99-Derived Agonist Ligands Inhibit Fibronectin-Induced Activation of β1 Integrin through the Protein Kinase A/SHP2/Extracellular Signal-Regulated Kinase/PTPN12/Focal Adhesion Kinase Signaling Pathway.
P2860
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P2860
Endothelial destabilization by angiopoietin-2 via integrin β1 activation.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Endothelial destabilization by angiopoietin-2 via integrin β1 activation.
@en
type
label
Endothelial destabilization by angiopoietin-2 via integrin β1 activation.
@en
prefLabel
Endothelial destabilization by angiopoietin-2 via integrin β1 activation.
@en
P2093
P2860
P50
P356
P1476
Endothelial destabilization by angiopoietin-2 via integrin β1 activation
@en
P2093
Laura Hakanpaa
Lauri Eklund
Prson Gautam
Tuomas Sipila
P2860
P2888
P356
10.1038/NCOMMS6962
P407
P577
2015-01-30T00:00:00Z