The human DEK oncogene stimulates β-catenin signaling, invasion and mammosphere formation in breast cancer. - Wikidata - wikimedia - TriplyDB

The human DEK oncogene stimulates β-catenin signaling, invasion and mammosphere formation in breast cancer.

The human DEK oncogene stimulates β-catenin signaling, invasion and mammosphere formation in breast cancer.

http://www.wikidata.org/entity/Q35050767

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Dissecting the Potential Interplay of DEK Functions in Inflammation and Cancer The DEK oncogene is a target of steroid hormone receptor signaling in breast cancer Intercellular trafficking of the nuclear oncoprotein DEK.DEK associates with tumor stage and outcome in HPV16 positive oropharyngeal squamous cell carcinoma.Overexpression of the human DEK oncogene reprograms cellular metabolism and promotes glycolysis DEK promotes HPV-positive and -negative head and neck cancer cell proliferation.Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer.The DEK oncogene promotes cellular proliferation through paracrine Wnt signaling in Ron receptor-positive breast cancers DEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer.The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.Future directions and treatment strategies for head and neck squamous cell carcinomas DEK is required for homologous recombination repair of DNA breaks.DEK protein level is a biomarker of CD138positive normal and malignant plasma cells.Stacking the DEK: from chromatin topology to cancer stem cells.Overexpression of DEK is an indicator of poor prognosis in patients with gastric adenocarcinoma.DEK depletion negatively regulates Rho/ROCK/MLC pathway in non-small cell lung cancer.The role of DEK protein in hepatocellular carcinoma for progression and prognosis.The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners.Critical role of DEK and its regulation in tumorigenesis and metastasis of hepatocellular carcinoma.Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer Concise review: role of DEK in stem/progenitor cell biology IRAK1 is a novel DEK transcriptional target and is essential for head and neck cancer cell survival.Site-specific methylated reporter constructs for functional analysis of DNA methylation.The DEK oncoprotein and its emerging roles in gene regulation.Inhibiting epidermal growth factor receptor signalling potentiates mesenchymal-epithelial transition of breast cancer stem cells and their responsiveness to anticancer drugs.A role for intracellular and extracellular DEK in regulating hematopoiesis.Expression profile of genes regulated by curcumin in Y79 retinoblastoma cells.DEK over-expression promotes mitotic defects and micronucleus formation.HGFL-mediated RON signaling supports breast cancer stem cell phenotypes via activation of non-canonical β-catenin signaling.DEK regulates hematopoietic stem engraftment and progenitor cell proliferation.MMP1, MMP9, and COX2 expressions in promonocytes are induced by breast cancer cells and correlate with collagen degradation, transformation-like morphological changes in MCF-10A acini, and tumor aggressiveness.DEK promoted EMT and angiogenesis through regulating PI3K/AKT/mTOR pathway in triple-negative breast cancer.Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in a Case-Control Study of Patients with Head and Neck Squamous Cell Carcinoma.Neuroanatomical Distribution of DEK Protein in Corticolimbic Circuits Associated with Learning and Memory in Adult Male and Female Mice.The nuclear DEK interactome supports multi-functionality.The potential predictive value of DEK expression for neoadjuvant chemoradiotherapy response in locally advanced rectal cancer.Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence.Speckle-type POZ protein is negatively associated with malignancies and inhibits cell proliferation and migration in liver cancer.TFEB-VEGFA (6p21.1) co-amplified renal cell carcinoma: a distinct entity with potential implications for clinical management.Oncogene DEK is highly expressed in lung cancerous tissues and positively regulates cell proliferation as well as invasion.

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The human DEK oncogene stimulates β-catenin signaling, invasion and mammosphere formation in breast cancer.

http://www.wikidata.org/entity/Q35050767

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2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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The human DEK oncogene stimula ...... re formation in breast cancer.

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The human DEK oncogene stimula ...... re formation in breast cancer.

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type

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The human DEK oncogene stimula ...... re formation in breast cancer.

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The human DEK oncogene stimula ...... re formation in breast cancer.

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The human DEK oncogene stimula ...... re formation in breast cancer.

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The human DEK oncogene stimula ...... re formation in breast cancer.

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K A Wikenheiser-Brokamp

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L M Privette Vinnedge

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P K Wagh

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R McClaine

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S E Waltz

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S I Wells

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Transcriptional activation by AP-2alpha is modulated by the oncogene DEK

The protein encoded by the proto-oncogene DEK changes the topology of chromatin and reduces the efficiency of DNA replication in a chromatin-specific manner

Prospective identification of tumorigenic breast cancer cells

The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

Gene expression profiling predicts clinical outcome of breast cancer

A gene-expression signature as a predictor of survival in breast cancer

Analyzing real-time PCR data by the comparative C(T) method

Subcellular localization of the human proto-oncogene protein DEK

The ubiquitous chromatin protein DEK alters the structure of DNA by introducing positive supercoils

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2741-2752

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10.1038/ONC.2011.2

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24

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1012326949

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3117026

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