Polarized secretion of beta-amyloid precursor protein and amyloid beta-peptide in MDCK cells
about
PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor proteinLysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin SDeletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's diseaseAmyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta poresRole of the epithelial cell-specific clathrin adaptor complex AP-1B in cell polarityAxonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cellsRegulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding proteinTrafficking and proteolytic processing of APPInteraction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide.Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer's diseaseThe NH(2)-terminus of norepinephrine transporter contains a basolateral localization signal for epithelial cells.The beta-amyloid precursor protein (APP) and Alzheimer's disease: does the tail wag the dog?Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism.PAT1a modulates intracellular transport and processing of amyloid precursor protein (APP), APLP1, and APLP2.Significance of transcytosis in Alzheimer's disease: BACE1 takes the scenic route to axons.Intracellular amyloid precursor protein sorting and amyloid-β secretion are regulated by Src-mediated phosphorylation of Mint2The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movementPolarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals.Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons.Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis.Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptorsRole of two recently cloned rat liver GSH transporters in the ubiquitous transport of GSH in mammalian cells.Use of Caenorhabditis elegans as a model to study Alzheimer's disease and other neurodegenerative diseases.LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-beta peptide in a blood-brain barrier in vitro model.Retromer regulates postendocytic sorting of β-secretase in polarized Madin-Darby canine kidney cells.Polarized transport of Alzheimer amyloid precursor protein is mediated by adaptor protein complex AP1-1B.Solution studies and structural model of the extracellular domain of the human amyloid precursor protein.A pathogenic PrP mutation and doppel interfere with polarized sorting of the prion protein.The Alzheimer's disease sphinx: a riddle with plaques and tanglesApical sorting of beta-secretase limits amyloid beta-peptide production.Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence.The role of APP processing and trafficking pathways in the formation of amyloid beta-protein.Signal-dependent trafficking of beta-amyloid precursor protein-transferrin receptor chimeras in madin-darby canine kidney cells.Generation of Alzheimer amyloid beta peptide through nonspecific proteolysis.Alzheimer's disease betaA4 protein release and amyloid precursor protein sorting are regulated by alternative splicing.Polarized expression of GABA transporters in Madin-Darby canine kidney cells and cultured hippocampal neurons.Exchanging the extracellular domain of amyloid precursor protein for horseradish peroxidase does not interfere with alpha-secretase cleavage of the beta-amyloid region, but randomizes secretion in Madin-Darby canine kidney cells.Proteoglycans in polarized epithelial Madin-Darby canine kidney cells.
P2860
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P2860
Polarized secretion of beta-amyloid precursor protein and amyloid beta-peptide in MDCK cells
description
1994 nî lūn-bûn
@nan
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Polarized secretion of beta-am ...... oid beta-peptide in MDCK cells
@ast
Polarized secretion of beta-am ...... oid beta-peptide in MDCK cells
@en
type
label
Polarized secretion of beta-am ...... oid beta-peptide in MDCK cells
@ast
Polarized secretion of beta-am ...... oid beta-peptide in MDCK cells
@en
prefLabel
Polarized secretion of beta-am ...... oid beta-peptide in MDCK cells
@ast
Polarized secretion of beta-am ...... oid beta-peptide in MDCK cells
@en
P2093
P2860
P356
P1476
Polarized secretion of beta-am ...... oid beta-peptide in MDCK cells
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.4.1564
P407
P577
1994-02-01T00:00:00Z