Autoimmune regulator: from loss of function to autoimmunity.
about
E3 ubiquitin ligases and their control of T cell autoreactivityAire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-toleranceTSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentationPhysiologic self antigens rapidly capacitate autoimmune disease-specific polyclonal CD4+ CD25+ regulatory T cells.The role of physiological self-antigen in the acquisition and maintenance of regulatory T-cell function.The role of the thymus in tolerance.Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice.The impact of circulating dendritic cells on the development and differentiation of thymocytes.Free radical theory of autoimmunityAltering immune tolerance therapeutically: the power of negative thinking.Central and peripheral autoantigen presentation in immune tolerance.Self-representation in the thymus: an extended view.IP-10 and type 1 diabetes: a question of time and location.Mechanisms of immunological tolerance in central nervous system inflammatory demyelination.Thymic transcription of neurohypophysial and insulin-related genes: impact upon T-cell differentiation and self-tolerance.Prediction and prevention of type 1 diabetes: update on success of prediction and struggles at preventionCentral tolerance: good but imperfect.Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters.AIRE functions as an E3 ubiquitin ligaseCentral tolerance to tissue-specific antigens mediated by direct and indirect antigen presentationPromiscuous gene expression in thymic epithelial cells is regulated at multiple levelsMolecular mechanisms of autoimmunity.Advances in type I diabetes associated tolerance mechanisms.Galectin-1 is essential for the induction of MOG35-55 -based intravenous tolerance in experimental autoimmune encephalomyelitis.The regulatory role of dendritic cells in the induction and maintenance of T-cell tolerance.Autoimmune Regulator (AIRE) Is Expressed in Spermatogenic Cells, and It Altered the Expression of Several Nucleic-Acid-Binding and Cytoskeletal Proteins in Germ Cell 1 Spermatogonial (GC1-spg) Cells.Selective depletion of CD11c+ CD11b+ dendritic cells partially abrogates tolerogenic effects of intravenous MOG in murine EAE.Human skin cells support thymus-independent T cell developmentThymus-homing dendritic cells in central tolerance.Thymic self-antigen expression for the design of a negative/tolerogenic self-vaccine against type 1 diabetesSubcellular expression of autoimmune regulator is organized in a spatiotemporal manner.Human thymic stromal lymphopoietin promotes dendritic cell-mediated CD4+ T cell homeostatic expansion.Antigen-presenting cells expressing glutamate decarboxylase 67 were identified as epithelial cells in glutamate decarboxylase 67-GFP knock-in mouse thymus.Murine uterine decidualization is a novel function of autoimmune regulator-beyond immune tolerance.Functional domains of SP110 that modulate its transcriptional regulatory function and cellular translocation.A vestigial pathway for sex differences in immune regulation.
P2860
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P2860
Autoimmune regulator: from loss of function to autoimmunity.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Autoimmune regulator: from loss of function to autoimmunity.
@ast
Autoimmune regulator: from loss of function to autoimmunity.
@en
type
label
Autoimmune regulator: from loss of function to autoimmunity.
@ast
Autoimmune regulator: from loss of function to autoimmunity.
@en
prefLabel
Autoimmune regulator: from loss of function to autoimmunity.
@ast
Autoimmune regulator: from loss of function to autoimmunity.
@en
P2860
P356
P1433
P1476
Autoimmune regulator: from loss of function to autoimmunity
@en
P2093
Pitkänen J
P2860
P2888
P356
10.1038/SJ.GENE.6363929
P577
2003-01-01T00:00:00Z