The autoimmune regulator (AIRE) is a DNA-binding protein
about
Transcriptional regulation by AIRE: molecular mechanisms of central toleranceAutoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): a model disease to study molecular aspects of endocrine autoimmunityMolecular cloning and characterization of the mouse Acdp gene familyUbiquitin signaling in immune responsesOvarian autoimmune disease: clinical concepts and animal modelsNuclear-cytoplasmic shuttling of a RING-IBR protein RBCK1 and its functional interaction with nuclear body proteinsModulation of Aire regulates the expression of tissue-restricted antigensResolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation.Control of central and peripheral tolerance by Aire.Clues to immune tolerance: the monogenic autoimmune syndromesBoth polymorphic variable number of tandem repeats and autoimmune regulator modulate differential expression of insulin in human thymic epithelial cells.Addressing protein localization within the nucleus.Epidemiology and genetics of alopecia areata.Comparative transcriptome analysis to reveal genes involved in wheat hybrid necrosis.Autoimmune regulator: from loss of function to autoimmunity.Unmodified histone H3K4 and DNA-dependent protein kinase recruit autoimmune regulator to target genes.Self-representation in the thymus: an extended view.Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression.AIRE and APECED: molecular insights into an autoimmune disease.Immunity by ubiquitylation: a reversible process of modification.AIRE functions as an E3 ubiquitin ligaseMechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire.Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity.Human APECED; a Sick Thymus Syndrome?PHD finger of autoimmune regulator: an epigenetic link between the histone modifications and tissue-specific antigen expression in thymus.AIRE in the thymus and beyond.Models of aire-dependent gene regulation for thymic negative selection.Autoimmune Regulator (AIRE) Is Expressed in Spermatogenic Cells, and It Altered the Expression of Several Nucleic-Acid-Binding and Cytoskeletal Proteins in Germ Cell 1 Spermatogonial (GC1-spg) Cells.AIRE: From promiscuous molecular partnerships to promiscuous gene expression.Functional Domains of Autoimmune Regulator (AIRE) Modulate INS-VNTR Transcription in Human Thymic Epithelial Cells.Autoimmune regulator and self-tolerance - molecular and clinical aspects.AIRE activated tissue specific genes have histone modifications associated with inactive chromatinIdentification of ubiquitin ligase activity of RBCK1 and its inhibition by splice variant RBCK2 and protein kinase Cbeta.DNA-PK contributes to the phosphorylation of AIRE: importance in transcriptional activity.AIRE recruits P-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells.Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner.AIRE1A might be involved in cyclin B2 degradation in testicular lysates.Insights into immune tolerance from AIRE deficiency.Quantitative analysis of protein-protein interactions and post-translational modifications in rare immune populations.AIRE: a missing link to explain female susceptibility to autoimmune diseases.
P2860
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P2860
The autoimmune regulator (AIRE) is a DNA-binding protein
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The autoimmune regulator (AIRE) is a DNA-binding protein
@ast
The autoimmune regulator (AIRE) is a DNA-binding protein
@en
The autoimmune regulator (AIRE) is a DNA-binding protein
@en-gb
The autoimmune regulator (AIRE) is a DNA-binding protein
@nl
type
label
The autoimmune regulator (AIRE) is a DNA-binding protein
@ast
The autoimmune regulator (AIRE) is a DNA-binding protein
@en
The autoimmune regulator (AIRE) is a DNA-binding protein
@en-gb
The autoimmune regulator (AIRE) is a DNA-binding protein
@nl
prefLabel
The autoimmune regulator (AIRE) is a DNA-binding protein
@ast
The autoimmune regulator (AIRE) is a DNA-binding protein
@en
The autoimmune regulator (AIRE) is a DNA-binding protein
@en-gb
The autoimmune regulator (AIRE) is a DNA-binding protein
@nl
P2093
P2860
P3181
P356
P1476
The autoimmune regulator (AIRE) is a DNA-binding protein
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M104898200
P407
P577
2001-11-02T00:00:00Z