Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene - Wikidata - wikimedia - TriplyDB

Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene

Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene

http://www.wikidata.org/entity/Q35072027

about

APOE genotype and stress response - a mini review Common defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploring Proteolytic cleavage of apolipoprotein E4 as the keystone for the heightened risk associated with Alzheimer's disease Ushering in the study and treatment of preclinical Alzheimer disease Entorhinal cortical defects in Tg2576 mice are present as early as 2-4 months of age.Triad of Risk for Late Onset Alzheimer's: Mitochondrial Haplotype, APOE Genotype and Chromosomal Sex Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease A defect in the mitochondrial complex III, but not complex IV, triggers early ROS-dependent damage in defined brain regions.A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice.Neuroprotective Effects of Icariin on Brain Metabolism, Mitochondrial Functions, and Cognition in Triple-Transgenic Alzheimer's Disease Mice.Platelet cytochrome oxidase and citrate synthase activities in APOE ε4 carrier and non-carrier Alzheimer's disease patients.Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease.Estrogen: a master regulator of bioenergetic systems in the brain and body Low-level light therapy of the eye and brain White matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's disease The Alzheimer's disease mitochondrial cascade hypothesis Association of hypometabolism and amyloid levels in aging, normal subjects Is Alzheimer's disease a systemic disease?APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease.Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments.Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study.Characterizing the preclinical stages of Alzheimer's disease and the prospect of presymptomatic intervention.Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's disease using metabolomics.The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging Lifespan brain activity, β-amyloid, and Alzheimer's disease.Brain aging, Alzheimer's disease, and mitochondria.Different mechanisms of apolipoprotein E isoform-dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia.A combined effect of two Alzheimer's risk genes on medial temporal activity during executive attention in young adults.Childhood Learning Disabilities and Atypical Dementia: A Retrospective Chart Review APOE modifies the association between Aβ load and cognition in cognitively normal older adults.Reduced mitochondria cytochrome oxidase activity in adult children of mothers with Alzheimer's disease.Amyloid-Related Memory Decline in Preclinical Alzheimer's Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months.Demographic and Lifestyle Characteristics, but Not Apolipoprotein E Genotype, Are Associated with Intelligence among Young Chinese College Students.Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease.Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents The association between a polygenic Alzheimer score and cortical thickness in clinically normal subjects.Longitudinal modeling of cognitive aging and the TOMM40 effect.Early Life Epidemiology of Alzheimer's Disease--A Critical Review Apolipoprotein E, not fibrillar β-amyloid, reduces cerebral glucose metabolism in normal aging.

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P2860

Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene

http://www.wikidata.org/entity/Q35072027

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Reduced posterior cingulate mi ...... lzheimer's susceptibility gene

@ast

Reduced posterior cingulate mi ...... lzheimer's susceptibility gene

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type

label

Reduced posterior cingulate mi ...... lzheimer's susceptibility gene

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Reduced posterior cingulate mi ...... lzheimer's susceptibility gene

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Reduced posterior cingulate mi ...... lzheimer's susceptibility gene

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Reduced posterior cingulate mi ...... lzheimer's susceptibility gene

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JAD-2010-100129

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Journal of Alzheimer's Disease

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Reduced posterior cingulate mi ...... lzheimer's susceptibility gene

@en

P2093

Alex E Roher

http://www.w3.org/2001/XMLSchema#string

Andrew B Wolf

http://www.w3.org/2001/XMLSchema#string

Jason J Corneveaux

http://www.w3.org/2001/XMLSchema#string

Jon Valla

http://www.w3.org/2001/XMLSchema#string

Matthew J Huentelman

http://www.w3.org/2001/XMLSchema#string

Richard J Caselli

http://www.w3.org/2001/XMLSchema#string

Roy Yaari

http://www.w3.org/2001/XMLSchema#string

Yael Kusne

http://www.w3.org/2001/XMLSchema#string

P2860

Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease

A default mode of brain function

Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory

Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele

Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.

Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism.

Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer's Disease Neuroimaging Initiative (ADNI).

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

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307-313

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scholarly article

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10.3233/JAD-2010-100129

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1

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22

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2010-01-01T00:00:00Z

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20847408

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Alzheimer's disease

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3124564

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