Differential activation and trafficking of micro-opioid receptors in brain slices. - Wikidata - wikimedia - TriplyDB

Differential activation and trafficking of micro-opioid receptors in brain slices.

Differential activation and trafficking of micro-opioid receptors in brain slices.

http://www.wikidata.org/entity/Q35076051

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Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons Cell-autonomous regulation of Mu-opioid receptor recycling by substance P.Anti-analgesic effect of the mu/delta opioid receptor heteromer revealed by ligand-biased antagonism Opiate agonist-induced re-distribution of Wntless, a mu-opioid receptor interacting protein, in rat striatal neurons Muscarinic acetylcholine receptor modulation of mu (mu) opioid receptors in adult rat sphenopalatine ganglion neurons.Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors Opioid-induced long-term potentiation in the spinal cord is a presynaptic event.Desensitized D2 autoreceptors are resistant to trafficking.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling.Rapid delivery of internalized signaling receptors to the somatodendritic surface by sequence-specific local insertion.The role of beta-arrestin2 in the severity of antinociceptive tolerance and physical dependence induced by different opioid pain therapeutics.Opioid-induced mitogen-activated protein kinase signaling in rat enteric neurons following chronic morphine treatment.Activation of µ-opioid receptors and block of Kir3 potassium channels and NMDA receptor conductance by L- and D-methadone in rat locus coeruleus.Morphine induces μ opioid receptor endocytosis in guinea pig enteric neurons following prolonged receptor activation Opioid receptor desensitization: mechanisms and its link to tolerance In vivo opioid receptor heteromerization: where do we stand?β-Arrestin-2 knockout prevents development of cellular μ-opioid receptor tolerance but does not affect opioid-withdrawal-related adaptations in single PAG neurons.Change in functional selectivity of morphine with the development of antinociceptive tolerance.Does PKC activation increase the homologous desensitization of μ opioid receptors?Heteromerization of the μ- and δ-opioid receptors produces ligand-biased antagonism and alters μ-receptor trafficking A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks.Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to human Chronic methadone treatment shows a better cost/benefit ratio than chronic morphine in mice.Desensitization and trafficking of μ-opioid receptors in locus ceruleus neurons: modulation by kinases.Opioid receptor internalization contributes to dermorphin-mediated antinociception Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.Evidence that behavioral phenotypes of morphine in β-arr2-/- mice are due to the unmasking of JNK signaling.Agonist Binding and Desensitization of the μ-Opioid Receptor Is Modulated by Phosphorylation of the C-Terminal Tail Domain.Morphine desensitization and cellular tolerance are distinguished in rat locus ceruleus neurons.Modulating neuromodulation by receptor membrane traffic in the endocytic pathway.Opioid tolerance in methadone maintenance treatment: comparison of methadone and levomethadone in long-term treatment Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Ovarian steroids alter mu opioid receptor trafficking in hippocampal parvalbumin GABAergic interneurons Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection.Ligand-induced μ opioid receptor internalization in enteric neurons following chronic treatment with the opiate fentanyl Spontaneous inhibitory synaptic currents mediated by a G protein-coupled receptor Oxycodone-induced conditioned place preference and sensitization of locomotor activity in adolescent and adult mice.

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P2860

Differential activation and trafficking of micro-opioid receptors in brain slices.

http://www.wikidata.org/entity/Q35076051

description

2008 nî lūn-bûn

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2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2008 թվականի հուլիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Differential activation and trafficking of micro-opioid receptors in brain slices.

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Differential activation and trafficking of micro-opioid receptors in brain slices.

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type

label

Differential activation and trafficking of micro-opioid receptors in brain slices.

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Differential activation and trafficking of micro-opioid receptors in brain slices.

@en

prefLabel

Differential activation and trafficking of micro-opioid receptors in brain slices.

@ast

Differential activation and trafficking of micro-opioid receptors in brain slices.

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Molecular Pharmacology

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Differential activation and trafficking of micro-opioid receptors in brain slices.

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P2093

John Pintar

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John T Williams

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Malcolm J Low

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Nidia Quillinan

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Seksiri Arttamangkul

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P2860

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

Functional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptors

ScanImage: flexible software for operating laser scanning microscopes.

Tracking the opioid receptors on the way of desensitization

Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons

Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence

Knockin mice expressing fluorescent delta-opioid receptors uncover G protein-coupled receptor dynamics in vivo.

Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction.

Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal.

The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals.

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972-979

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10.1124/MOL.108.048512

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4

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74

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Mark von Zastrow

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5240839

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18612077

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3125947

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