Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. - Wikidata - wikimedia - TriplyDB

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions.

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions.

http://www.wikidata.org/entity/Q35076939

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Nek4 regulates entry into replicative senescence and the response to DNA damage in human fibroblasts Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathway Human telomerase and its regulation Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1 Smurf2 up-regulation activates telomere-dependent senescence Growth retardation and premature aging phenotypes in mice with disruption of the SNF2-like gene, PASG Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging Immortalization of mouse myogenic cells can occur without loss of p16INK4a, p19ARF, or p53 and is accelerated by inactivation of Bax Complex roles for telomeres and telomerase in breast carcinogenesis Value of Organoids from Comparative Epithelia Models Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.In Vitro Model of the Epidermis: Connecting Protein Function to 3D Structure The Importance of Physiologically Relevant Cell Lines for Studying Virus-Host Interactions Efficient genetic method for establishing Drosophila cell lines unlocks the potential to create lines of specific genotypes Malignant transformation of non-neoplastic Barrett's epithelial cells through well-defined genetic manipulations Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor Development and characterization of a new human hepatic cell line.A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence.H-ras expression in immortalized keratinocytes produces an invasive epithelium in cultured skin equivalents.The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence.Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.Phenotypic plasticity in normal breast derived epithelial cells.Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies.Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo.Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages.Cell senescence and cancer.Acid and bile salt-induced CDX2 expression differs in esophageal squamous cells from patients with and without Barrett's esophagus.Four faces of cellular senescence.Short hairpin RNA screen indicates that Klotho beta/FGF19 protein overcomes stasis in human colonic epithelial cells The essence of senescence.Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.Stable cellular senescence is associated with persistent DDR activation A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status Immortalized keratinocyte lines derived from human embryonic stem cells Senescence: does it all happen at the ends?Regulation of senescence in cancer and aging.Are there roles for brain cell senescence in aging and neurodegenerative disorders?Cancer-related inflammation and Barrett's carcinogenesis: interleukin-6 and STAT3 mediate apoptotic resistance in transformed Barrett's cells.Molecular regulation of melanocyte senescence.The identification of senescence-specific genes during the induction of senescence in prostate cancer cells.

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P2860

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions.

http://www.wikidata.org/entity/Q35076939

description

2001 nî lūn-bûn

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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի փետրվարին հրատարակված գիտական հոդված

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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name

Putative telomere-independent ...... inadequate growth conditions.

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Putative telomere-independent ...... inadequate growth conditions.

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type

label

Putative telomere-independent ...... inadequate growth conditions.

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Putative telomere-independent ...... inadequate growth conditions.

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Putative telomere-independent ...... inadequate growth conditions.

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Putative telomere-independent ...... inadequate growth conditions.

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Putative telomere-independent ...... inadequate growth conditions.

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B S Herbert

http://www.w3.org/2001/XMLSchema#string

C P Morales

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C Passons

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J M Rohde

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J W Shay

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R D Ramirez

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W E Wright

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P2860

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Extension of life-span by introduction of telomerase into normal human cells

Evidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cells

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

TRF2 Protects Human Telomeres from End-to-End Fusions

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

The serial cultivation of human diploid cell strains

Telomeres shorten during ageing of human fibroblasts

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

Serum amine oxidase activity contributes to crisis in mouse embryo cell lines.

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11230148

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312628

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