Binding interactions between soluble HIV envelope glycoproteins and quaternary-structure-specific monoclonal antibodies PG9 and PG16. - Wikidata - wikimedia - TriplyDB

Binding interactions between soluble HIV envelope glycoproteins and quaternary-structure-specific monoclonal antibodies PG9 and PG16.

Binding interactions between soluble HIV envelope glycoproteins and quaternary-structure-specific monoclonal antibodies PG9 and PG16.

http://www.wikidata.org/entity/Q35077716

about

Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10 A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies HIV-1 envelope proteins and V1/V2 domain scaffolds with mannose-5 to improve the magnitude and quality of protective antibody responses to HIV-1 Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs Envelope variants circulating as initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.Mass spectrometry approach and ELISA reveal the effect of codon optimization on N-linked glycosylation of HIV-1 gp120 Synergy in monoclonal antibody neutralization of HIV-1 pseudoviruses and infectious molecular clones.Sub-inhibitory concentrations of human α-defensin potentiate neutralizing antibodies against HIV-1 gp41 pre-hairpin intermediates in the presence of serum.A multivalent clade C HIV-1 Env trimer cocktail elicits a higher magnitude of neutralizing antibodies than any individual component.Functional characterization of two scFv-Fc antibodies from an HIV controller selected on soluble HIV-1 Env complexes: a neutralizing V3- and a trimer-specific gp41 antibody.Immunization of rabbits with highly purified, soluble, trimeric human immunodeficiency virus type 1 envelope glycoprotein induces a vigorous B cell response and broadly cross-reactive neutralization.Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors.Antigenicity and immunogenicity of a trimeric envelope protein from an Indian clade C HIV-1 isolate.Rationally Targeted Mutations at the V1V2 Domain of the HIV-1 Envelope to Augment Virus Neutralization by Anti-V1V2 Monoclonal Antibodies.Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein.HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120.Antigenicity and immunogenicity of RV144 vaccine AIDSVAX clade E envelope immunogen is enhanced by a gp120 N-terminal deletion.Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.Identification of an HIV-1 clade A envelope that exhibits broad antigenicity and neutralization sensitivity and elicits antibodies targeting three distinct epitopes.Isolation of HIV-1-reactive antibodies using cell surface-expressed gp160Δc(BaL.).Diverse recombinant HIV-1 Envs fail to activate B cells expressing the germline B cell receptors of the broadly neutralizing anti-HIV-1 antibodies PG9 and 447-52D.Candidate antibody-based therapeutics against HIV-1.Role of human immunodeficiency virus type 1 envelope structure in the induction of broadly neutralizing antibodies.Characterization of structural features and diversity of variable-region determinants of related quaternary epitopes recognized by human and rhesus macaque monoclonal antibodies possessing unusually potent neutralizing activities.Efficacy of broadly neutralizing monoclonal antibody PG16 in HIV-infected humanized mice.Functional Stability of HIV-1 Envelope Trimer Affects Accessibility to Broadly Neutralizing Antibodies at its Apex.Trimeric HIV Env provides epitope occlusion mediated by hypervariable loops Display of the HIV envelope protein at the yeast cell surface for immunogen development

P2860

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P2860

Binding interactions between soluble HIV envelope glycoproteins and quaternary-structure-specific monoclonal antibodies PG9 and PG16.

http://www.wikidata.org/entity/Q35077716

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Binding interactions between s ...... lonal antibodies PG9 and PG16.

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Binding interactions between s ...... lonal antibodies PG9 and PG16.

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type

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Binding interactions between s ...... lonal antibodies PG9 and PG16.

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Binding interactions between s ...... lonal antibodies PG9 and PG16.

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Binding interactions between s ...... lonal antibodies PG9 and PG16.

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Binding interactions between s ...... lonal antibodies PG9 and PG16.

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P1433

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P2860

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P1433

Journal of Virology

P1476

Binding interactions between s ...... lonal antibodies PG9 and PG16.

@en

P2093

Della Friend

http://www.w3.org/2001/XMLSchema#string

George Sellhorn

http://www.w3.org/2001/XMLSchema#string

Hengyu Xu

http://www.w3.org/2001/XMLSchema#string

Katharine Ellingson

http://www.w3.org/2001/XMLSchema#string

Leonidas Stamatatos

http://www.w3.org/2001/XMLSchema#string

Roland K Strong

http://www.w3.org/2001/XMLSchema#string

Thaddeus M Davenport

http://www.w3.org/2001/XMLSchema#string

Zachary Caldwell

http://www.w3.org/2001/XMLSchema#string

Zane Kraft

http://www.w3.org/2001/XMLSchema#string

P2860

Few and far between: how HIV may be evading antibody avidity

High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1

Human Immunodeficiency Virus Type 1 Subtype B Ancestral Envelope Protein Is Functional and Elicits Neutralizing Antibodies in Rabbits Similar to Those Elicited by a Circulating Subtype B Envelope

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.

B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

P304

7095-7107

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scholarly article

P356

10.1128/JVI.00411-11

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P407

P433

14

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P478

85

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2011-05-04T00:00:00Z

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51099213

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21543501

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3126577

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